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1xnq

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[[Image:1xnq.gif|left|200px]]
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{{STRUCTURE_1xnq| PDB=1xnq | SCENE= }}
{{STRUCTURE_1xnq| PDB=1xnq | SCENE= }}
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'''Structure of an Inosine-Adenine Wobble Base Pair Complex in the Context of the Decoding Center'''
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===Structure of an Inosine-Adenine Wobble Base Pair Complex in the Context of the Decoding Center===
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==Overview==
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Here we report the crystal structures of I.C and I.A wobble base pairs in the context of the ribosomal decoding center, clearly showing that the I.A base pair is of an I(anti).A(anti) conformation, as predicted by Crick. Additionally, the structures enable the observation of changes in the anticodon to allow purine-purine base pairing, the 'widest' base pair geometry allowed in the wobble position.
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(as it appears on PubMed at http://www.pubmed.gov), where 15558050 is the PubMed ID number.
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{{ABSTRACT_PUBMED_15558050}}
==About this Structure==
==About this Structure==
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[[Category: Ribosome]]
[[Category: Ribosome]]
[[Category: Translation]]
[[Category: Translation]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sat May 3 15:16:19 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Jul 28 10:07:30 2008''

Revision as of 07:07, 28 July 2008

Image:1xnq.png

Template:STRUCTURE 1xnq

Structure of an Inosine-Adenine Wobble Base Pair Complex in the Context of the Decoding Center

Template:ABSTRACT PUBMED 15558050

About this Structure

1XNQ is a Protein complex structure of sequences from Thermus thermophilus. Full crystallographic information is available from OCA.

Reference

Structure of a purine-purine wobble base pair in the decoding center of the ribosome., Murphy FV 4th, Ramakrishnan V, Nat Struct Mol Biol. 2004 Dec;11(12):1251-2. Epub 2004 Nov 21. PMID:15558050

Page seeded by OCA on Mon Jul 28 10:07:30 2008

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