This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.

Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


2bqv

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Line 1: Line 1:
-
[[Image:2bqv.gif|left|200px]]
+
{{Seed}}
 +
[[Image:2bqv.png|left|200px]]
<!--
<!--
Line 9: Line 10:
{{STRUCTURE_2bqv| PDB=2bqv | SCENE= }}
{{STRUCTURE_2bqv| PDB=2bqv | SCENE= }}
-
'''HIV-1 PROTEASE IN COMPLEX WITH INHIBITOR AHA455'''
+
===HIV-1 PROTEASE IN COMPLEX WITH INHIBITOR AHA455===
-
==Overview==
+
<!--
-
Novel HIV-1 protease inhibitors encompassing a tertiary alcohol as part of the transition-state mimicking unit have been synthesized. Variation of the P1'-P3' residues and alteration of the tertiary alcohol absolute stereochemistry afforded 10 inhibitors. High potencies for the compounds with (S)-configuration at the carbon carrying the tertiary hydroxyl group were achieved with Ki values down to 2.4 nM. X-ray crystallographic data for a representative compound in complex with HIV-1 protease are presented.
+
The line below this paragraph, {{ABSTRACT_PUBMED_16335934}}, adds the Publication Abstract to the page
 +
(as it appears on PubMed at http://www.pubmed.gov), where 16335934 is the PubMed ID number.
 +
-->
 +
{{ABSTRACT_PUBMED_16335934}}
==About this Structure==
==About this Structure==
Line 34: Line 38:
[[Category: Hydrolase complex]]
[[Category: Hydrolase complex]]
[[Category: Inhibitor]]
[[Category: Inhibitor]]
-
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sat May 3 20:39:59 2008''
+
 
 +
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Jul 28 11:07:54 2008''

Revision as of 08:08, 28 July 2008

Image:2bqv.png

Template:STRUCTURE 2bqv

HIV-1 PROTEASE IN COMPLEX WITH INHIBITOR AHA455

Template:ABSTRACT PUBMED 16335934

About this Structure

2BQV is a Single protein structure of sequence from Human immunodeficiency virus 1. Full crystallographic information is available from OCA.

Reference

A new class of HIV-1 protease inhibitors containing a tertiary alcohol in the transition-state mimicking scaffold., Ekegren JK, Unge T, Safa MZ, Wallberg H, Samuelsson B, Hallberg A, J Med Chem. 2005 Dec 15;48(25):8098-102. PMID:16335934

Page seeded by OCA on Mon Jul 28 11:07:54 2008

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/2bqv"
Personal tools