1s2x

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{{STRUCTURE_1s2x| PDB=1s2x | SCENE= }}
{{STRUCTURE_1s2x| PDB=1s2x | SCENE= }}
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'''Crystal structure of Cag-Z from Helicobacter pylori'''
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===Crystal structure of Cag-Z from Helicobacter pylori===
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==Overview==
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CagZ, a 23 kDa protein encoded by the cagZ gene (HP0526) of the cag pathogenicity island of Helicobacter pylori, has been cloned, over-expressed, purified and its three-dimensional structure determined. The protein consists of a single compact L-shaped domain, composed of seven alpha-helices including about 70% of the total residues. Three-dimensional homology searches did not reveal structural homologues, and CagZ can be considered representative of a new protein fold. The presence of a disordered C-terminal tail and the nature of the molecular surface suggest that CagZ may participate in the interaction of effector proteins with one or more components of the H.pylori type IV secretion system on the cytoplasmic side of the inner membrane.
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(as it appears on PubMed at http://www.pubmed.gov), where 15223328 is the PubMed ID number.
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{{ABSTRACT_PUBMED_15223328}}
==About this Structure==
==About this Structure==
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[[Category: Helicobacter pylori]]
[[Category: Helicobacter pylori]]
[[Category: Type iv secretion system]]
[[Category: Type iv secretion system]]
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Revision as of 08:08, 28 July 2008

Image:1s2x.png

Template:STRUCTURE 1s2x

Crystal structure of Cag-Z from Helicobacter pylori

Template:ABSTRACT PUBMED 15223328

About this Structure

1S2X is a Single protein structure of sequence from Helicobacter pylori. Full crystallographic information is available from OCA.

Reference

Crystal structure of CagZ, a protein from the Helicobacter pylori pathogenicity island that encodes for a type IV secretion system., Cendron L, Seydel A, Angelini A, Battistutta R, Zanotti G, J Mol Biol. 2004 Jul 16;340(4):881-9. PMID:15223328

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