1rxa

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[[Image:1rxa.gif|left|200px]]
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{{Seed}}
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{{STRUCTURE_1rxa| PDB=1rxa | SCENE= }}
{{STRUCTURE_1rxa| PDB=1rxa | SCENE= }}
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'''CRYSTAL STRUCTURE OF R(CCCCGGGG) IN TWO DISTINCT LATTICES'''
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===CRYSTAL STRUCTURE OF R(CCCCGGGG) IN TWO DISTINCT LATTICES===
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==Overview==
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The structure of the RNA octamer r(C4G4) has been determined in two different crystal forms. The conformations of the RNA duplex in the rhombohedral and hexagonal lattices display only minimal deviations, demonstrating that the RNA double helix is considerably less deformable than the DNA double helix. For the first time the crystal structures of an A-RNA and an A-DNA with identical sequence can now be compared. The large number of ordered water molecules observed in the minor groove of the RNA duplex suggests that an important contribution to its higher rigidity derives from the improved hydration due to the presence of the 2'-hydroxyl groups. Our finding that the conformation of the RNA double helix is virtually unaffected by different crystal packing modes provides evidence that proteins may not alter the conformation of RNA stem regions in a significant way.
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The line below this paragraph, {{ABSTRACT_PUBMED_7779802}}, adds the Publication Abstract to the page
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(as it appears on PubMed at http://www.pubmed.gov), where 7779802 is the PubMed ID number.
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{{ABSTRACT_PUBMED_7779802}}
==About this Structure==
==About this Structure==
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[[Category: A-rna]]
[[Category: A-rna]]
[[Category: Double helix]]
[[Category: Double helix]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sat May 3 08:00:59 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Jul 28 11:59:02 2008''

Revision as of 08:59, 28 July 2008

Image:1rxa.png

Template:STRUCTURE 1rxa

CRYSTAL STRUCTURE OF R(CCCCGGGG) IN TWO DISTINCT LATTICES

Template:ABSTRACT PUBMED 7779802

About this Structure

Full crystallographic information is available from OCA.

Reference

The crystal structure of r(CCCCGGGG) in two distinct lattices., Portmann S, Usman N, Egli M, Biochemistry. 1995 Jun 13;34(23):7569-75. PMID:7779802

Page seeded by OCA on Mon Jul 28 11:59:02 2008

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