This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
1mn8
From Proteopedia
OCA (Talk | contribs)
(New page: 200px<br /><applet load="1mn8" size="450" color="white" frame="true" align="right" spinBox="true" caption="1mn8, resolution 1.0Å" /> '''Structure of Moloney ...)
Next diff →
Revision as of 19:25, 20 November 2007
|
Structure of Moloney Murine Leukaemia Virus Matrix Protein
Overview
Matrix proteins associated with the viral membrane are important in the, formation of the viral particle and in virus maturation. The 1.0 A crystal, structure of the ecotropic Gammaretrovirus Moloney murine leukemia virus, (M-MuLV) matrix protein reveals the conserved topology of other retroviral, matrix proteins, despite undetectable sequence similarity. The N terminus, (normally myristylated) is exposed and adjacent to a basic surface patch, features likely to contribute to membrane binding. The four proteins in, the asymmetric unit make varied contacts. The M-MuLV matrix structure is, intermediate, between those of the lentiviruses and other retroviruses., The protein fold appears to be maintained, in part, by the conservation of, side chain packing, which may provide a useful tool for searching for weak, distant similarities in proteins.
About this Structure
1MN8 is a Single protein structure of sequence from Moloney murine leukemia virus. Full crystallographic information is available from OCA.
Reference
Atomic resolution structure of Moloney murine leukemia virus matrix protein and its relationship to other retroviral matrix proteins., Riffel N, Harlos K, Iourin O, Rao Z, Kingsman A, Stuart D, Fry E, Structure. 2002 Dec;10(12):1627-36. PMID:12467570
Page seeded by OCA on Tue Nov 20 21:32:50 2007
