This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.

Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


1t2r

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Line 1: Line 1:
-
[[Image:1t2r.gif|left|200px]]
+
{{Seed}}
 +
[[Image:1t2r.png|left|200px]]
<!--
<!--
Line 9: Line 10:
{{STRUCTURE_1t2r| PDB=1t2r | SCENE= }}
{{STRUCTURE_1t2r| PDB=1t2r | SCENE= }}
-
'''Structural basis for 3' end recognition of nucleic acids by the Drosophila Argonaute 2 PAZ domain'''
+
===Structural basis for 3' end recognition of nucleic acids by the Drosophila Argonaute 2 PAZ domain===
-
==Overview==
+
<!--
-
We describe the solution structures of the Argonaute2 PAZ domain bound to RNA and DNA oligonucleotides. The structures reveal a unique mode of single-stranded nucleic acid binding in which the two 3'-terminal nucleotides are buried in a hydrophobic cleft. We propose that the PAZ domain contributes to the specific recognition of siRNAs by providing a binding pocket for their characteristic two-nucleotide 3' overhangs.
+
The line below this paragraph, {{ABSTRACT_PUBMED_15156196}}, adds the Publication Abstract to the page
 +
(as it appears on PubMed at http://www.pubmed.gov), where 15156196 is the PubMed ID number.
 +
-->
 +
{{ABSTRACT_PUBMED_15156196}}
==About this Structure==
==About this Structure==
-
1T2R is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Drosophila_melanogaster Drosophila melanogaster]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1T2R OCA].
+
1T2R is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Drosophila_melanogaster Drosophila melanogaster]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1T2R OCA].
==Reference==
==Reference==
Line 28: Line 32:
[[Category: Nucleic acid binding protein]]
[[Category: Nucleic acid binding protein]]
[[Category: Rna]]
[[Category: Rna]]
-
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sat May 3 09:26:38 2008''
+
 
 +
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Jul 28 12:21:00 2008''

Revision as of 09:21, 28 July 2008

Image:1t2r.png

Template:STRUCTURE 1t2r

Structural basis for 3' end recognition of nucleic acids by the Drosophila Argonaute 2 PAZ domain

Template:ABSTRACT PUBMED 15156196

About this Structure

1T2R is a Single protein structure of sequence from Drosophila melanogaster. Full experimental information is available from OCA.

Reference

Nucleic acid 3'-end recognition by the Argonaute2 PAZ domain., Lingel A, Simon B, Izaurralde E, Sattler M, Nat Struct Mol Biol. 2004 Jun;11(6):576-7. Epub 2004 May 23. PMID:15156196

Page seeded by OCA on Mon Jul 28 12:21:00 2008

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/1t2r"
Personal tools