This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.

Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


1zfd

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Line 1: Line 1:
-
[[Image:1zfd.jpg|left|200px]]
+
{{Seed}}
 +
[[Image:1zfd.png|left|200px]]
<!--
<!--
Line 9: Line 10:
{{STRUCTURE_1zfd| PDB=1zfd | SCENE= }}
{{STRUCTURE_1zfd| PDB=1zfd | SCENE= }}
-
'''SWI5 ZINC FINGER DOMAIN 2, NMR, 45 STRUCTURES'''
+
===SWI5 ZINC FINGER DOMAIN 2, NMR, 45 STRUCTURES===
-
==Overview==
+
<!--
-
This paper describes the detailed three-dimensional structures of two zinc-finger domains from the yeast transcription factor SWI5, calculated using the results of the n.m.r. experiments described in the accompanying paper. The structure of finger 2 is essentially similar to those previously obtained by others for isolated, synthetic single zinc-finger domains in solution, and for the three zinc-finger peptide Zif268 in its crystalline complex with DNA. The N-terminal half of the sequence forms a two-stranded, irregular beta-sheet containing both of the metal-binding cysteine residues, while the remainder of the structure forms a helix. Approximately the first half of this helix is alpha-helical, whereas the C-terminal portion, including the two metal-binding histidine residues, is 3(10) helical. Four invariant hydrophobic residues form a core to the structure. In contrast to all previously described structures of zinc-finger domains, finger 1 has an additional strand in the beta-sheet, formed by residues N-terminal to the formal start of the finger motif. This additional strand plays a role in stabilising the folded form of finger 1, since a two-finger peptide lacking the N-terminal residues showed folded structure in finger 2 but not in finger 1.
+
The line below this paragraph, {{ABSTRACT_PUBMED_1453468}}, adds the Publication Abstract to the page
 +
(as it appears on PubMed at http://www.pubmed.gov), where 1453468 is the PubMed ID number.
 +
-->
 +
{{ABSTRACT_PUBMED_1453468}}
==About this Structure==
==About this Structure==
-
1ZFD is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1ZFD OCA].
+
1ZFD is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1ZFD OCA].
==Reference==
==Reference==
Line 29: Line 33:
[[Category: Dna binding motif]]
[[Category: Dna binding motif]]
[[Category: Zinc finger dna binding domain]]
[[Category: Zinc finger dna binding domain]]
-
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sat May 3 17:33:22 2008''
+
 
 +
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Jul 28 12:29:15 2008''

Revision as of 09:29, 28 July 2008

Image:1zfd.png

Template:STRUCTURE 1zfd

SWI5 ZINC FINGER DOMAIN 2, NMR, 45 STRUCTURES

Template:ABSTRACT PUBMED 1453468

About this Structure

1ZFD is a Single protein structure of sequence from Saccharomyces cerevisiae. Full experimental information is available from OCA.

Reference

Solution structures of two zinc-finger domains from SWI5 obtained using two-dimensional 1H nuclear magnetic resonance spectroscopy. A zinc-finger structure with a third strand of beta-sheet., Neuhaus D, Nakaseko Y, Schwabe JW, Klug A, J Mol Biol. 1992 Nov 20;228(2):637-51. PMID:1453468

Page seeded by OCA on Mon Jul 28 12:29:15 2008

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/1zfd"
Personal tools