2by7

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[[Image:2by7.gif|left|200px]]
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{{Seed}}
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[[Image:2by7.png|left|200px]]
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{{STRUCTURE_2by7| PDB=2by7 | SCENE= }}
{{STRUCTURE_2by7| PDB=2by7 | SCENE= }}
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'''IS RADIATION DAMAGE DEPENDENT ON THE DOSE-RATE USED DURING MACROMOLECULAR CRYSTALLOGRAPHY DATA COLLECTION'''
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===IS RADIATION DAMAGE DEPENDENT ON THE DOSE-RATE USED DURING MACROMOLECULAR CRYSTALLOGRAPHY DATA COLLECTION===
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==Overview==
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This paper focuses on the radiation-damage effects when applying the same total X-ray dose to protein crystals at different dose rates. These experiments have been performed on both a selenomethionated protein and on bovine trypsin using dose rates that span nearly two orders of magnitude. The results show no clear dose-rate effect on the global indicators of radiation damage, but a small measurable dose-rate effect could be found when studying specific radiation damage. It is hypothesized that this observed dose-rate effect relates to differences in the steady-state free-radical concentration.
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The line below this paragraph, {{ABSTRACT_PUBMED_16421442}}, adds the Publication Abstract to the page
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(as it appears on PubMed at http://www.pubmed.gov), where 16421442 is the PubMed ID number.
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{{ABSTRACT_PUBMED_16421442}}
==About this Structure==
==About this Structure==
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[[Category: Timmins, J.]]
[[Category: Timmins, J.]]
[[Category: Data collection,radiation damage,dose-rate,synchrotron radiation,hydrolase]]
[[Category: Data collection,radiation damage,dose-rate,synchrotron radiation,hydrolase]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sat May 3 20:57:36 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Jul 28 13:48:27 2008''

Revision as of 10:48, 28 July 2008

Image:2by7.png

Template:STRUCTURE 2by7

IS RADIATION DAMAGE DEPENDENT ON THE DOSE-RATE USED DURING MACROMOLECULAR CRYSTALLOGRAPHY DATA COLLECTION

Template:ABSTRACT PUBMED 16421442

About this Structure

2BY7 is a Single protein structure of sequence from Bos taurus. Full crystallographic information is available from OCA.

Reference

Is radiation damage dependent on the dose rate used during macromolecular crystallography data collection?, Leiros HK, Timmins J, Ravelli RB, McSweeney SM, Acta Crystallogr D Biol Crystallogr. 2006 Feb;62(Pt 2):125-32. Epub 2006, Jan 18. PMID:16421442

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