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2c0t

From Proteopedia

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[[Image:2c0t.gif|left|200px]]
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{{Seed}}
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[[Image:2c0t.png|left|200px]]
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{{STRUCTURE_2c0t| PDB=2c0t | SCENE= }}
{{STRUCTURE_2c0t| PDB=2c0t | SCENE= }}
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'''SRC FAMILY KINASE HCK WITH BOUND INHIBITOR A-641359'''
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===SRC FAMILY KINASE HCK WITH BOUND INHIBITOR A-641359===
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==Overview==
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We describe the identification, SAR, and pharmacology of the src-family selective lck inhibitor A-770041 that prolongs the survival of major histocompatibility mismatched allografts in models of solid organ transplant rejection for greater than 65 days.
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The line below this paragraph, {{ABSTRACT_PUBMED_16216497}}, adds the Publication Abstract to the page
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(as it appears on PubMed at http://www.pubmed.gov), where 16216497 is the PubMed ID number.
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{{ABSTRACT_PUBMED_16216497}}
==About this Structure==
==About this Structure==
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[[Category: Transferase]]
[[Category: Transferase]]
[[Category: Tyrosine-protein kinase]]
[[Category: Tyrosine-protein kinase]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sat May 3 21:04:23 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Jul 28 13:53:41 2008''

Revision as of 10:53, 28 July 2008

Image:2c0t.png

Template:STRUCTURE 2c0t

SRC FAMILY KINASE HCK WITH BOUND INHIBITOR A-641359

Template:ABSTRACT PUBMED 16216497

About this Structure

2C0T is a Single protein structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

Discovery of A-770041, a src-family selective orally active lck inhibitor that prevents organ allograft rejection., Burchat A, Borhani DW, Calderwood DJ, Hirst GC, Li B, Stachlewitz RF, Bioorg Med Chem Lett. 2006 Jan 1;16(1):118-22. Epub 2005 Oct 10. PMID:16216497

Page seeded by OCA on Mon Jul 28 13:53:41 2008

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