361d

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[[Image:361d.gif|left|200px]]
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{{Seed}}
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{{STRUCTURE_361d| PDB=361d | SCENE= }}
{{STRUCTURE_361d| PDB=361d | SCENE= }}
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'''CRYSTAL STRUCTURE OF DOMAIN E OF THERMUS FLAVUS 5S RRNA: A HELICAL RNA-STRUCTURE INCLUDING A TETRALOOP'''
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===CRYSTAL STRUCTURE OF DOMAIN E OF THERMUS FLAVUS 5S RRNA: A HELICAL RNA-STRUCTURE INCLUDING A TETRALOOP===
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==Overview==
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The synthetic RNA fragment 5'-CUGGGCGG(GCGA)CCGCCUGG (nucleotides in parentheses indicate the loop region) corresponds to the natural sequence of domain E from nucleotides 79-97 of the Thermus flavus 5S rRNA including a hairpin loop. The RNA structure determined at 3.0 A and refined to an R-value of 24.1% also represents the first X-ray structure GNRA tetraloop. The loop is in distinctly different conformation from other GNRA tetraloops analyzed by NMR. The conformation of the two molecules in the asymmetric unit is influenced and stabilized by specific intermolecular contacts. The structural features presented here give evidence for the ability of RNA molecules to adapt to specific environments.
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(as it appears on PubMed at http://www.pubmed.gov), where 9650592 is the PubMed ID number.
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{{ABSTRACT_PUBMED_9650592}}
==About this Structure==
==About this Structure==
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[[Category: Single strand]]
[[Category: Single strand]]
[[Category: Tetraloop]]
[[Category: Tetraloop]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun May 4 20:17:18 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Jul 28 14:27:57 2008''

Revision as of 11:28, 28 July 2008

Image:361d.png

Template:STRUCTURE 361d

CRYSTAL STRUCTURE OF DOMAIN E OF THERMUS FLAVUS 5S RRNA: A HELICAL RNA-STRUCTURE INCLUDING A TETRALOOP

Template:ABSTRACT PUBMED 9650592

About this Structure

Full crystallographic information is available from OCA.

Reference

Crystal structure of domain E of Thermus flavus 5S rRNA: a helical RNA structure including a hairpin loop., Perbandt M, Nolte A, Lorenz S, Bald R, Betzel C, Erdmann VA, FEBS Lett. 1998 Jun 12;429(2):211-5. PMID:9650592

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