1pzu

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Line 1: Line 1:
-
[[Image:1pzu.gif|left|200px]]
+
{{Seed}}
 +
[[Image:1pzu.png|left|200px]]
<!--
<!--
Line 9: Line 10:
{{STRUCTURE_1pzu| PDB=1pzu | SCENE= }}
{{STRUCTURE_1pzu| PDB=1pzu | SCENE= }}
-
'''An asymmetric NFAT1-RHR homodimer on a pseudo-palindromic, Kappa-B site'''
+
===An asymmetric NFAT1-RHR homodimer on a pseudo-palindromic, Kappa-B site===
-
==Overview==
+
<!--
-
The crystal structure of the NFAT1 Rel homology region (RHR) bound to a pseudo-palindromic DNA site reveals an asymmetric dimer interaction between the RHR-C domains, unrelated to the contact seen in Rel dimers such as NF kappa B. Binding studies with a form of the NFAT1 RHR defective in the dimer contact show loss of cooperativity and demonstrate that the same interaction is present in solution. The structure we have determined may correspond to a functional NFAT binding mode at palindromic sites of genes induced during the anergic response to weak TCR signaling.
+
The line below this paragraph, {{ABSTRACT_PUBMED_12949491}}, adds the Publication Abstract to the page
 +
(as it appears on PubMed at http://www.pubmed.gov), where 12949491 is the PubMed ID number.
 +
-->
 +
{{ABSTRACT_PUBMED_12949491}}
==About this Structure==
==About this Structure==
Line 33: Line 37:
[[Category: Protein-dna complex]]
[[Category: Protein-dna complex]]
[[Category: Transcription factor]]
[[Category: Transcription factor]]
-
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sat May 3 05:41:32 2008''
+
 
 +
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Jul 28 14:59:15 2008''

Revision as of 11:59, 28 July 2008

Image:1pzu.png

Template:STRUCTURE 1pzu

An asymmetric NFAT1-RHR homodimer on a pseudo-palindromic, Kappa-B site

Template:ABSTRACT PUBMED 12949491

About this Structure

1PZU is a Single protein structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

An asymmetric NFAT1 dimer on a pseudo-palindromic kappa B-like DNA site., Jin L, Sliz P, Chen L, Macian F, Rao A, Hogan PG, Harrison SC, Nat Struct Biol. 2003 Oct;10(10):807-11. Epub 2003 Aug 31. PMID:12949491

Page seeded by OCA on Mon Jul 28 14:59:15 2008

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/1pzu"
Personal tools