1n56
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(New page: 200px<br /><applet load="1n56" size="450" color="white" frame="true" align="right" spinBox="true" caption="1n56, resolution 2.4Å" /> '''Y-family DNA polymera...)
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Revision as of 19:51, 20 November 2007
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Y-family DNA polymerase Dpo4 in complex with DNA containing abasic lesion
Overview
Studies on several recently discovered error-prone DNA polymerases reveal, novel structures that may explain the low fidelity of this general class, of enzymes, a number of which are involved in the replicative bypass, (translesion synthesis) of base damage in DNA.
About this Structure
1N56 is a Single protein structure of sequence from Sulfolobus solfataricus with MG, CA and ATP as ligands. Full crystallographic information is available from OCA.
Reference
Error-prone DNA polymerases: novel structures and the benefits of infidelity., Friedberg EC, Fischhaber PL, Kisker C, Cell. 2001 Oct 5;107(1):9-12. PMID:11595180
Page seeded by OCA on Tue Nov 20 21:58:15 2007
Categories: Single protein | Sulfolobus solfataricus | Boudsocq, F. | Ling, H. | Woodgate, R. | Yang, W. | ATP | CA | MG | Dna lesion bypass | Dna polymerase | Protein-dna complex | Y-family
