1qpx

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Line 1: Line 1:
-
[[Image:1qpx.jpg|left|200px]]
+
{{Seed}}
 +
[[Image:1qpx.png|left|200px]]
<!--
<!--
Line 9: Line 10:
{{STRUCTURE_1qpx| PDB=1qpx | SCENE= }}
{{STRUCTURE_1qpx| PDB=1qpx | SCENE= }}
-
'''CRYSTAL STRUCTURES OF SELF-CAPPING PAPD CHAPERONE HOMODIMERS'''
+
===CRYSTAL STRUCTURES OF SELF-CAPPING PAPD CHAPERONE HOMODIMERS===
-
==Overview==
+
<!--
-
PapD is an immunoglobulin-like chaperone that mediates the assembly of P pili in uropathogenic strains of Escherichia coli. It binds and caps interactive surfaces on pilus subunits to prevent their premature associations in the periplasm. We elucidated the structural basis of a mechanism whereby PapD also interacts with itself, capping its own subunit binding surface. Crystal structures of dimeric forms of PapD revealed that this self-capping mechanism involves a rearrangement and ordering of the C2-D2 and F1-G1 loops upon dimerization which might ensure that a stable dimer is not formed in solution in spite of a relatively large dimer interface. An analysis of site directed mutations revealed that chaperone dimerization requires the same surface that is otherwise used to bind subunits.
+
The line below this paragraph, {{ABSTRACT_PUBMED_10393968}}, adds the Publication Abstract to the page
 +
(as it appears on PubMed at http://www.pubmed.gov), where 10393968 is the PubMed ID number.
 +
-->
 +
{{ABSTRACT_PUBMED_10393968}}
==About this Structure==
==About this Structure==
Line 29: Line 33:
[[Category: Chaperone]]
[[Category: Chaperone]]
[[Category: Immunoglobulin fold]]
[[Category: Immunoglobulin fold]]
-
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sat May 3 06:34:04 2008''
+
 
 +
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Jul 28 16:07:20 2008''

Revision as of 13:07, 28 July 2008

Image:1qpx.png

Template:STRUCTURE 1qpx

CRYSTAL STRUCTURES OF SELF-CAPPING PAPD CHAPERONE HOMODIMERS

Template:ABSTRACT PUBMED 10393968

About this Structure

1QPX is a Single protein structure of sequence from Escherichia coli. Full crystallographic information is available from OCA.

Reference

Structural basis of chaperone self-capping in P pilus biogenesis., Hung DL, Pinkner JS, Knight SD, Hultgren SJ, Proc Natl Acad Sci U S A. 1999 Jul 6;96(14):8178-83. PMID:10393968

Page seeded by OCA on Mon Jul 28 16:07:20 2008

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/1qpx"
Personal tools