1nz0

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[[Image:1nz0.gif|left|200px]]
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{{STRUCTURE_1nz0| PDB=1nz0 | SCENE= }}
{{STRUCTURE_1nz0| PDB=1nz0 | SCENE= }}
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'''RNASE P PROTEIN FROM THERMOTOGA MARITIMA'''
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===RNASE P PROTEIN FROM THERMOTOGA MARITIMA===
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==Overview==
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The structure of RNase P protein from the hyperthermophilic bacterium Thermotoga maritima was determined at 1.2-A resolution by using x-ray crystallography. This protein structure is from an ancestral-type RNase P and bears remarkable similarity to the recently determined structures of RNase P proteins from bacteria that have the distinct, Bacillus type of RNase P. These two types of protein span the extent of bacterial RNase P diversity, so the results generalize the structure of the bacterial RNase P protein. The broad phylogenetic conservation of structure and distribution of potential RNA-binding elements in the RNase P proteins indicate that all of these homologous proteins bind to their cognate RNAs primarily by interaction with the phylogenetically conserved core of the RNA. The protein is found to dimerize through an extensive, well-ordered interface. This dimerization may reflect a mechanism of thermal stability of the protein before assembly with the RNA moiety of the holoenzyme.
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(as it appears on PubMed at http://www.pubmed.gov), where 12799461 is the PubMed ID number.
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{{ABSTRACT_PUBMED_12799461}}
==About this Structure==
==About this Structure==
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[[Category: Rnase]]
[[Category: Rnase]]
[[Category: Structural genomic]]
[[Category: Structural genomic]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sat May 3 03:09:25 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Jul 28 16:14:10 2008''

Revision as of 13:14, 28 July 2008

Image:1nz0.png

Template:STRUCTURE 1nz0

RNASE P PROTEIN FROM THERMOTOGA MARITIMA

Template:ABSTRACT PUBMED 12799461

About this Structure

1NZ0 is a Single protein structure of sequence from Thermotoga maritima. Full crystallographic information is available from OCA.

Reference

High-resolution structure of RNase P protein from Thermotoga maritima., Kazantsev AV, Krivenko AA, Harrington DJ, Carter RJ, Holbrook SR, Adams PD, Pace NR, Proc Natl Acad Sci U S A. 2003 Jun 24;100(13):7497-502. Epub 2003 Jun 10. PMID:12799461

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