1nci
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(New page: 200px<br /><applet load="1nci" size="450" color="white" frame="true" align="right" spinBox="true" caption="1nci, resolution 2.1Å" /> '''STRUCTURAL BASIS OF C...)
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Revision as of 20:01, 20 November 2007
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STRUCTURAL BASIS OF CELL-CELL ADHESION BY CADHERINS
Overview
Crystal structures of the amino-terminal domain of N-cadherin provide a, picture at the atomic level of a specific adhesive contact between cells., A repeated set of dimer interfaces is common to the structure in three, lattices. These interactions combine to form a linear zipper of molecules, that mirrors the linear structure of the intracellular filaments with, which cadherins associate. This cell-adhesion zipper may provide a, mechanism to marshal individual molecular adhesive interactions into, strong bonds between cells.
About this Structure
1NCI is a Single protein structure of sequence from Mus musculus with IUM as ligand. Full crystallographic information is available from OCA.
Reference
Structural basis of cell-cell adhesion by cadherins., Shapiro L, Fannon AM, Kwong PD, Thompson A, Lehmann MS, Grubel G, Legrand JF, Als-Nielsen J, Colman DR, Hendrickson WA, Nature. 1995 Mar 23;374(6520):327-37. PMID:7885471
Page seeded by OCA on Tue Nov 20 22:08:13 2007
