2q2z

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Line 1: Line 1:
-
[[Image:2q2z.jpg|left|200px]]
+
{{Seed}}
 +
[[Image:2q2z.png|left|200px]]
<!--
<!--
Line 9: Line 10:
{{STRUCTURE_2q2z| PDB=2q2z | SCENE= }}
{{STRUCTURE_2q2z| PDB=2q2z | SCENE= }}
-
'''Crystal Structure of KSP in Complex with Inhibitor 22'''
+
===Crystal Structure of KSP in Complex with Inhibitor 22===
-
==Overview==
+
<!--
-
Inspired by previous efforts in the pyrazolobenzoxazine class of KSP inhibitors, the design and synthesis of 1,4-diaryl-4,5-dihydropyrazole inhibitors of KSP are described. Crystallographic evidence of binding mode and in vivo potency data is also highlighted.
+
The line below this paragraph, {{ABSTRACT_PUBMED_17766111}}, adds the Publication Abstract to the page
 +
(as it appears on PubMed at http://www.pubmed.gov), where 17766111 is the PubMed ID number.
 +
-->
 +
{{ABSTRACT_PUBMED_17766111}}
==About this Structure==
==About this Structure==
Line 26: Line 30:
[[Category: Ksp]]
[[Category: Ksp]]
[[Category: Ksp-inhibitor complex]]
[[Category: Ksp-inhibitor complex]]
-
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun May 4 14:13:49 2008''
+
 
 +
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Jul 28 17:18:37 2008''

Revision as of 14:18, 28 July 2008

Template:STRUCTURE 2q2z

Crystal Structure of KSP in Complex with Inhibitor 22

Template:ABSTRACT PUBMED 17766111

About this Structure

2Q2Z is a Single protein structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

Kinesin spindle protein (KSP) inhibitors. Part 8: Design and synthesis of 1,4-diaryl-4,5-dihydropyrazoles as potent inhibitors of the mitotic kinesin KSP., Roecker AJ, Coleman PJ, Mercer SP, Schreier JD, Buser CA, Walsh ES, Hamilton K, Lobell RB, Tao W, Diehl RE, South VJ, Davide JP, Kohl NE, Yan Y, Kuo LC, Li C, Fernandez-Metzler C, Mahan EA, Prueksaritanont T, Hartman GD, Bioorg Med Chem Lett. 2007 Oct 15;17(20):5677-82. Epub 2007 Aug 21. PMID:17766111

Page seeded by OCA on Mon Jul 28 17:18:37 2008

Proteopedia Page Contributors and Editors (what is this?)

OCA

Personal tools