1nik
From Proteopedia
OCA (Talk | contribs)
(New page: 200px<br /><applet load="1nik" size="450" color="white" frame="true" align="right" spinBox="true" caption="1nik, resolution 4.10Å" /> '''Wild Type RNA Polyme...)
Next diff →
Revision as of 20:10, 20 November 2007
|
Wild Type RNA Polymerase II
Overview
The x-ray structure of complete RNA polymerase II from Saccharomyces, cerevisiae has been determined, including a heterodimer of subunits Rpb4, and Rpb7 not present in previous "core" polymerase II structures. The, heterodimer maintains the polymerase in the conformation of a transcribing, complex, may bind RNA as it emerges from the enzyme, and is in a position, to interact with general transcription factors and the Mediator of, transcriptional regulation.
About this Structure
1NIK is a Protein complex structure of sequences from Saccharomyces cerevisiae with ZN as ligand. Active as DNA-directed RNA polymerase, with EC number 2.7.7.6 Full crystallographic information is available from OCA.
Reference
Complete, 12-subunit RNA polymerase II at 4.1-A resolution: implications for the initiation of transcription., Bushnell DA, Kornberg RD, Proc Natl Acad Sci U S A. 2003 Jun 10;100(12):6969-73. Epub 2003 May 13. PMID:12746498
Page seeded by OCA on Tue Nov 20 22:17:30 2007
