2ong

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{{STRUCTURE_2ong| PDB=2ong | SCENE= }}
{{STRUCTURE_2ong| PDB=2ong | SCENE= }}
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'''Crystal Structure of of limonene synthase with 2-fluorogeranyl diphosphate (FGPP).'''
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===Crystal Structure of of limonene synthase with 2-fluorogeranyl diphosphate (FGPP).===
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==Overview==
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The crystal structure of (4S)-limonene synthase from Mentha spic ata, a metal ion-dependent monoterpene cyclase that catalyzes the coupled isomerization and cyclization of geranyl diphosphate, is reported at 2.7-A; resolution in two forms liganded to the substrate and intermediate analogs, 2-fluorogeranyl diphosphate and 2-fluorolinalyl diphosphate, respectively. The implications of these findings are described for domain interactions in the homodimer and for changes in diphosphate-metal ion coordination and substrate binding conformation in the course of the multistep reaction.
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(as it appears on PubMed at http://www.pubmed.gov), where 17372193 is the PubMed ID number.
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{{ABSTRACT_PUBMED_17372193}}
==About this Structure==
==About this Structure==
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[[Category: Monoterpene cyclase]]
[[Category: Monoterpene cyclase]]
[[Category: Monoterpene synthase]]
[[Category: Monoterpene synthase]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun May 4 11:15:51 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Jul 28 18:59:41 2008''

Revision as of 15:59, 28 July 2008

Image:2ong.png

Template:STRUCTURE 2ong

Crystal Structure of of limonene synthase with 2-fluorogeranyl diphosphate (FGPP).

Template:ABSTRACT PUBMED 17372193

About this Structure

2ONG is a Single protein structure of sequence from Mentha spicata. Full crystallographic information is available from OCA.

Reference

Structure of limonene synthase, a simple model for terpenoid cyclase catalysis., Hyatt DC, Youn B, Zhao Y, Santhamma B, Coates RM, Croteau RB, Kang C, Proc Natl Acad Sci U S A. 2007 Mar 27;104(13):5360-5. Epub 2007 Mar 19. PMID:17372193

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