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1nmp

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(New page: 200px<br /><applet load="1nmp" size="450" color="white" frame="true" align="right" spinBox="true" caption="1nmp, resolution 2.20&Aring;" /> '''Structural genomics,...)
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Revision as of 20:16, 20 November 2007

Image:1nmp.jpg

1nmp, resolution 2.20Å

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Structural genomics, ybgI protein, unknown function

Overview

BACKGROUND: The protein encoded by the gene ybgI was chosen as a target, for a structural genomics project emphasizing the relation of protein, structure to function. RESULTS: The structure of the ybgI protein is a, toroid composed of six polypeptide chains forming a trimer of dimers. Each, polypeptide chain binds two metal ions on the inside of the toroid., CONCLUSION: The toroidal structure is comparable to that of some proteins, that are involved in DNA metabolism. The di-nuclear metal site could imply, that the specific function of this protein is as a hydrolase-oxidase, enzyme.

About this Structure

1NMP is a Single protein structure of sequence from Escherichia coli, and escherichia coli o157:h7 with MG as ligand. Full crystallographic information is available from OCA.

Reference

Crystal structure of Escherichia coli protein ybgI, a toroidal structure with a dinuclear metal site., Ladner JE, Obmolova G, Teplyakov A, Howard AJ, Khil PP, Camerini-Otero RD, Gilliland GL, BMC Struct Biol. 2003 Sep 30;3:7. PMID:14519207

Page seeded by OCA on Tue Nov 20 22:23:52 2007

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