2rgf

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{{STRUCTURE_2rgf| PDB=2rgf | SCENE= }}
{{STRUCTURE_2rgf| PDB=2rgf | SCENE= }}
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'''RBD OF RAL GUANOSINE-NUCLEOTIDE EXCHANGE FACTOR (PROTEIN), NMR, 10 STRUCTURES'''
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===RBD OF RAL GUANOSINE-NUCLEOTIDE EXCHANGE FACTOR (PROTEIN), NMR, 10 STRUCTURES===
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==Overview==
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The solution structure of the Ras-binding domain (RBD) of Ral guanine-nucleotide exchange factor RalGEF was solved by NMR spectroscopy. The overall structure is similar to that of Raf-RBD, another effector of Ras, although the sequence identity is only 13%. 15N chemical shifts changes in the complex of RalGEF-RBD with Ras indicate an interaction similar to the intermolecular beta-sheet observed for the complex between Ras and Raf-RBD.
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{{ABSTRACT_PUBMED_9302994}}
==About this Structure==
==About this Structure==
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2RGF is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2RGF OCA].
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2RGF is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2RGF OCA].
==Reference==
==Reference==
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[[Category: Ras-binding domain]]
[[Category: Ras-binding domain]]
[[Category: Rbd]]
[[Category: Rbd]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun May 4 16:52:11 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Jul 28 19:33:34 2008''

Revision as of 16:33, 28 July 2008

Template:STRUCTURE 2rgf

RBD OF RAL GUANOSINE-NUCLEOTIDE EXCHANGE FACTOR (PROTEIN), NMR, 10 STRUCTURES

Template:ABSTRACT PUBMED 9302994

About this Structure

2RGF is a Single protein structure of sequence from Homo sapiens. Full experimental information is available from OCA.

Reference

Structure of the Ras-binding domain of RalGEF and implications for Ras binding and signalling., Geyer M, Herrmann C, Wohlgemuth S, Wittinghofer A, Kalbitzer HR, Nat Struct Biol. 1997 Sep;4(9):694-9. PMID:9302994

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