1zye

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[[Image:1zye.gif|left|200px]]
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{{Seed}}
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[[Image:1zye.png|left|200px]]
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{{STRUCTURE_1zye| PDB=1zye | SCENE= }}
{{STRUCTURE_1zye| PDB=1zye | SCENE= }}
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'''Crystal strucutre analysis of Bovine Mitochondrial Peroxiredoxin III'''
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===Crystal strucutre analysis of Bovine Mitochondrial Peroxiredoxin III===
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==Overview==
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A crystal structure is reported for the C168S mutant of a typical 2-Cys peroxiredoxin III (Prx III) from bovine mitochondria at a resolution of 3.3 A. Prx III is present as a two-ring catenane comprising two interlocking dodecameric toroids that are assembled from basic dimeric units. Each ring has an external diameter of 150 A and encompasses a central cavity that is 70 A in width. The concatenated dodecamers are inclined at an angle of 55 degrees, which provides a large contact surface between the rings. Dimer-dimer contacts involved in toroid formation are hydrophobic in nature, whereas the 12 areas of contact between interlocked rings arise from polar interactions. These two major modes of subunit interaction provide important insights into possible mechanisms of catenane formation.
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The line below this paragraph, {{ABSTRACT_PUBMED_16271889}}, adds the Publication Abstract to the page
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(as it appears on PubMed at http://www.pubmed.gov), where 16271889 is the PubMed ID number.
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{{ABSTRACT_PUBMED_16271889}}
==About this Structure==
==About this Structure==
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[[Category: Dodecamer]]
[[Category: Dodecamer]]
[[Category: Peroxiredoxin]]
[[Category: Peroxiredoxin]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sat May 3 18:14:05 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Jul 28 19:38:46 2008''

Revision as of 16:38, 28 July 2008

Image:1zye.png

Template:STRUCTURE 1zye

Crystal strucutre analysis of Bovine Mitochondrial Peroxiredoxin III

Template:ABSTRACT PUBMED 16271889

About this Structure

1ZYE is a Single protein structure of sequence from Bos taurus. Full crystallographic information is available from OCA.

Reference

Bovine mitochondrial peroxiredoxin III forms a two-ring catenane., Cao Z, Roszak AW, Gourlay LJ, Lindsay JG, Isaacs NW, Structure. 2005 Nov;13(11):1661-4. PMID:16271889

Page seeded by OCA on Mon Jul 28 19:38:46 2008

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