1tof

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{{STRUCTURE_1tof| PDB=1tof | SCENE= }}
{{STRUCTURE_1tof| PDB=1tof | SCENE= }}
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'''THIOREDOXIN H (OXIDIZED FORM), NMR, 23 STRUCTURES'''
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===THIOREDOXIN H (OXIDIZED FORM), NMR, 23 STRUCTURES===
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==Overview==
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NMR solution structures of a cytosolic plant thioredoxin h (112 amino acids, 11.7 kDa) from the green alga Chlamydonmonas reinhardtii have been calculated on the basis of 1904 NMR distance restraints, which include 90 distances used to restrain 45 hydrogen bonds, and 44 phi dihedral restraints. The structure of C. reinhardtii thioredoxin h was solved in its oxidised form, and the ensemble of 23 converged structures superpose to the geometric average structure with an atomic rmsd of 0.080 nm +/- 0.016 for the (N, C(alpha), C) backbone atoms of residues 4-110. Comparisons with other thioredoxins, such as thioredoxin from the bacterium Escherichia coli, thioredoxin 2 from a cyanobacterium of the Anabaena genus, and human thioredoxin, showed that thioredoxin h models share more structural features with human thioredoxin than with other bacterial thioredoxins. Examination of the accessible surface around the redoxactive peptide sequence indicates that a potent thioredoxin-h-substrate interaction could be similar to the vertebrate thioredoxin-substrate interactions.
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{{ABSTRACT_PUBMED_9030762}}
==About this Structure==
==About this Structure==
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1TOF is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Chlamydomonas_reinhardtii Chlamydomonas reinhardtii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1TOF OCA].
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1TOF is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Chlamydomonas_reinhardtii Chlamydomonas reinhardtii]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1TOF OCA].
==Reference==
==Reference==
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[[Category: Electron transport]]
[[Category: Electron transport]]
[[Category: Oxidoreductase]]
[[Category: Oxidoreductase]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sat May 3 10:11:11 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Jul 28 20:27:01 2008''

Revision as of 17:27, 28 July 2008

Image:1tof.png

Template:STRUCTURE 1tof

THIOREDOXIN H (OXIDIZED FORM), NMR, 23 STRUCTURES

Template:ABSTRACT PUBMED 9030762

About this Structure

1TOF is a Single protein structure of sequence from Chlamydomonas reinhardtii. Full experimental information is available from OCA.

Reference

NMR solution structure of an oxidised thioredoxin h from the eukaryotic green alga Chlamydomonas reinhardtii., Mittard V, Blackledge MJ, Stein M, Jacquot JP, Marion D, Lancelin JM, Eur J Biochem. 1997 Jan 15;243(1-2):374-83. PMID:9030762

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