2adw

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Line 1: Line 1:
-
[[Image:2adw.gif|left|200px]]
+
{{Seed}}
 +
[[Image:2adw.png|left|200px]]
<!--
<!--
Line 9: Line 10:
{{STRUCTURE_2adw| PDB=2adw | SCENE= }}
{{STRUCTURE_2adw| PDB=2adw | SCENE= }}
-
'''Crystal strucutre of Echinomycin-(ACGTACGT)2 solved by SAD'''
+
===Crystal strucutre of Echinomycin-(ACGTACGT)2 solved by SAD===
-
==Overview==
+
<!--
-
A new crystal form was obtained for the complex between (ACGTACGT)2 and echinomycin and X-ray data were collected to 1.6 A. The structure was phased by the SAD method based on a single unexpected anomalous scatterer that could be identified as a mixture of nickel and zinc by measurements of the anomalous scattering at different wavelengths. This cation is coordinated by two guanines from two different duplexes and four water molecules. The structure resembles previously reported crystal structures of DNA-echinomycin complexes, except that three of the eight base pairs flanking the echinomycin bisintercalator sites have the Watson-Crick rather than the Hoogsteen configuration. Hoogsteen binding was found for the corresponding base pairs of the crystallographically independent duplex, indicating that the two configurations are very close in energy.
+
The line below this paragraph, {{ABSTRACT_PUBMED_16552143}}, adds the Publication Abstract to the page
 +
(as it appears on PubMed at http://www.pubmed.gov), where 16552143 is the PubMed ID number.
 +
-->
 +
{{ABSTRACT_PUBMED_16552143}}
==About this Structure==
==About this Structure==
Line 24: Line 28:
[[Category: Bisintercalator]]
[[Category: Bisintercalator]]
[[Category: Hoogsteen/watson-crick]]
[[Category: Hoogsteen/watson-crick]]
-
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sat May 3 18:55:21 2008''
+
 
 +
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Jul 28 20:42:22 2008''

Revision as of 17:42, 28 July 2008

Image:2adw.png

Template:STRUCTURE 2adw

Crystal strucutre of Echinomycin-(ACGTACGT)2 solved by SAD

Template:ABSTRACT PUBMED 16552143

About this Structure

Full crystallographic information is available from OCA.

Reference

Serendipitous SAD phasing of an echinomycin-(ACGTACGT)2 bisintercalation complex., Cuesta-Seijo JA, Weiss MS, Sheldrick GM, Acta Crystallogr D Biol Crystallogr. 2006 Apr;62(Pt 4):417-24. Epub 2006, Mar 18. PMID:16552143

Page seeded by OCA on Mon Jul 28 20:42:22 2008

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/2adw"
Personal tools