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1qz8

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[[Image:1qz8.gif|left|200px]]
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[[Image:1qz8.png|left|200px]]
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{{STRUCTURE_1qz8| PDB=1qz8 | SCENE= }}
{{STRUCTURE_1qz8| PDB=1qz8 | SCENE= }}
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'''Crystal structure of SARS coronavirus NSP9'''
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===Crystal structure of SARS coronavirus NSP9===
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==Overview==
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The recently identified etiological agent of the severe acute respiratory syndrome (SARS) belongs to Coronaviridae (CoV), a family of viruses replicating by a poorly understood mechanism. Here, we report the crystal structure at 2.7-A resolution of nsp9, a hitherto uncharacterized subunit of the SARS-CoV replicative polyproteins. We show that SARS-CoV nsp9 is a single-stranded RNA-binding protein displaying a previously unreported, oligosaccharide/oligonucleotide fold-like fold. The presence of this type of protein has not been detected in the replicative complexes of RNA viruses, and its presence may reflect the unique and complex CoV viral replication/transcription machinery.
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(as it appears on PubMed at http://www.pubmed.gov), where 15007178 is the PubMed ID number.
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{{ABSTRACT_PUBMED_15007178}}
==About this Structure==
==About this Structure==
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[[Category: Replication]]
[[Category: Replication]]
[[Category: Sar]]
[[Category: Sar]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sat May 3 06:53:02 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Jul 28 20:51:19 2008''

Revision as of 17:51, 28 July 2008

Image:1qz8.png

Template:STRUCTURE 1qz8

Crystal structure of SARS coronavirus NSP9

Template:ABSTRACT PUBMED 15007178

About this Structure

1QZ8 is a Single protein structure of sequence from Human sars coronavirus. Full crystallographic information is available from OCA.

Reference

The severe acute respiratory syndrome-coronavirus replicative protein nsp9 is a single-stranded RNA-binding subunit unique in the RNA virus world., Egloff MP, Ferron F, Campanacci V, Longhi S, Rancurel C, Dutartre H, Snijder EJ, Gorbalenya AE, Cambillau C, Canard B, Proc Natl Acad Sci U S A. 2004 Mar 16;101(11):3792-6. Epub 2004 Mar 8. PMID:15007178

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