2v0f

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{{STRUCTURE_2v0f| PDB=2v0f | SCENE= }}
{{STRUCTURE_2v0f| PDB=2v0f | SCENE= }}
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'''BRK DOMAIN FROM HUMAN CHD7'''
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===BRK DOMAIN FROM HUMAN CHD7===
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==Overview==
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CHD7 is a member of the chromodomain helicase DNA binding domain (CHD) family of ATP-dependent chromatin remodelling enzymes. It is mutated in CHARGE syndrome, a multiple congenital anomaly condition. CHD7 is one of a subset of CHD proteins, unique to metazoans that contain the BRK domain, a protein module also found in the Brahma/BRG1 family of helicases. We describe here the NMR solution structure of the two BRK domains of CHD7. Each domain has a compact betabetaalphabeta fold. The second domain has a C-terminal extension consisting of two additional helices. The structure differs from those of other domains present in chromatin-associated proteins.
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(as it appears on PubMed at http://www.pubmed.gov), where 17603073 is the PubMed ID number.
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{{ABSTRACT_PUBMED_17603073}}
==About this Structure==
==About this Structure==
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2V0F is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2V0F OCA].
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2V0F is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2V0F OCA].
==Reference==
==Reference==
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun May 4 17:57:30 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Jul 28 20:52:42 2008''

Revision as of 17:52, 28 July 2008

Image:2v0f.png

Template:STRUCTURE 2v0f

BRK DOMAIN FROM HUMAN CHD7

Template:ABSTRACT PUBMED 17603073

About this Structure

2V0F is a Single protein structure of sequence from Homo sapiens. Full experimental information is available from OCA.

Reference

Solution structure of the BRK domains from CHD7., Allen MD, Religa TL, Freund SM, Bycroft M, J Mol Biol. 2007 Aug 31;371(5):1135-40. Epub 2007 Jun 9. PMID:17603073

Page seeded by OCA on Mon Jul 28 20:52:42 2008

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