1pcl

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{{STRUCTURE_1pcl| PDB=1pcl | SCENE= }}
{{STRUCTURE_1pcl| PDB=1pcl | SCENE= }}
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'''UNUSUAL STRUCTURAL FEATURES IN THE PARALLEL BETA-HELIX IN PECTATE LYASES'''
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===UNUSUAL STRUCTURAL FEATURES IN THE PARALLEL BETA-HELIX IN PECTATE LYASES===
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==Overview==
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BACKGROUND: A new type of domain structure, an all parallel beta class, has recently been observed in two pectate lyases, PelC and PelE. The atomic models have been analyzed to determine whether the new tertiary fold exhibits unusual structural features. RESULTS: The polypeptide backbone exhibits no new types of secondary structural elements. However, novel features occur in the amino acid side chain interactions. The side chain atoms form linear stacks that include asparagine ladders, serine stacks, aliphatic stacks, and ringed-residue stacks. A new type of beta-sandwich between parallel beta-sheets is observed with properties that are more characteristic of antiparallel beta-sheets. CONCLUSION: An analysis of the PelC and PelE structures, belonging to an all parallel beta structural class, reveals novel amino acid side chain interactions, a new type of beta-sandwich and an atypical amino acid composition of parallel beta-sheets. The findings are relevant to three-dimensional structural predictions.
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(as it appears on PubMed at http://www.pubmed.gov), where 8081738 is the PubMed ID number.
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{{ABSTRACT_PUBMED_8081738}}
==About this Structure==
==About this Structure==
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[[Category: Keen, N T.]]
[[Category: Keen, N T.]]
[[Category: Lietzke, S E.]]
[[Category: Lietzke, S E.]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sat May 3 04:56:25 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Jul 28 21:28:27 2008''

Revision as of 18:28, 28 July 2008

Image:1pcl.png

Template:STRUCTURE 1pcl

UNUSUAL STRUCTURAL FEATURES IN THE PARALLEL BETA-HELIX IN PECTATE LYASES

Template:ABSTRACT PUBMED 8081738

About this Structure

1PCL is a Single protein structure of sequence from Erwinia chrysanthemi. Full crystallographic information is available from OCA.

Reference

Unusual structural features in the parallel beta-helix in pectate lyases., Yoder MD, Lietzke SE, Jurnak F, Structure. 1993 Dec 15;1(4):241-51. PMID:8081738

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