1ugl

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[[Image:1ugl.jpg|left|200px]]
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[[Image:1ugl.png|left|200px]]
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{{STRUCTURE_1ugl| PDB=1ugl | SCENE= }}
{{STRUCTURE_1ugl| PDB=1ugl | SCENE= }}
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'''Solution structure of S8-SP11'''
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===Solution structure of S8-SP11===
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==Overview==
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Many flowering plants possess a self-incompatibility system to prevent inbreeding. In Brassica rapa, self/non-self recognition in mating is established through S-haplotype-specific interactions between stigma receptors and S-locus protein 11 (SP11, also called S-locus cysteine-rich protein) that is encoded at the highly polymorphic S-locus. Here we describe the solution structure of the SP11 protein of the S8-haplotype (S8-SP11), which specifically binds to the stigma factor of the same haplotype. It folds into an alpha/beta sandwich structure that resembles those of plant defensins. Residues important for structural integrity are highly conserved among the allelic SP11s, suggesting the existence of a common folding pattern. Structure-based sequence alignment and homology modeling of allelic SP11 identified a hyper-variable (HV) region, which is thought to form a loop that bulges out from the body of the protein that is amenable to solvent exposure. We suggest that the HV region could serve as a specific binding site for the stigma receptor.
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The line below this paragraph, {{ABSTRACT_PUBMED_12835321}}, adds the Publication Abstract to the page
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(as it appears on PubMed at http://www.pubmed.gov), where 12835321 is the PubMed ID number.
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{{ABSTRACT_PUBMED_12835321}}
==About this Structure==
==About this Structure==
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1UGL is a [[Single protein]] structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1UGL OCA].
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1UGL is a [[Single protein]] structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1UGL OCA].
==Reference==
==Reference==
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[[Category: Sp11]]
[[Category: Sp11]]
[[Category: Structural genomic]]
[[Category: Structural genomic]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sat May 3 11:12:00 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Jul 28 23:43:09 2008''

Revision as of 20:43, 28 July 2008

Image:1ugl.png

Template:STRUCTURE 1ugl

Solution structure of S8-SP11

Template:ABSTRACT PUBMED 12835321

About this Structure

1UGL is a Single protein structure. Full experimental information is available from OCA.

Reference

Structure of the male determinant factor for Brassica self-incompatibility., Mishima M, Takayama S, Sasaki K, Jee JG, Kojima C, Isogai A, Shirakawa M, J Biol Chem. 2003 Sep 19;278(38):36389-95. Epub 2003 Jun 30. PMID:12835321

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