1udv

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{{STRUCTURE_1udv| PDB=1udv | SCENE= }}
{{STRUCTURE_1udv| PDB=1udv | SCENE= }}
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'''Crystal structure of the hyperthermophilic archaeal dna-binding protein Sso10b2 at 1.85 A'''
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===Crystal structure of the hyperthermophilic archaeal dna-binding protein Sso10b2 at 1.85 A===
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==Overview==
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The crystal structure of a small, basic DNA binding protein, Sso10b2, from the thermoacidophilic archaeon Sulfolobus solfataricus was determined by the Zn multiwavelength anomalous diffraction method and refined to 1.85 A resolution. The 89-amino-acid protein adopts a betaalphabetaalphabetabeta topology. The structure is similar to that of Sso10b1 (also called Alba) from the same organism. However, Sso10b2 contains an arginine-rich loop RDRRR motif, which may play an important role in nucleic acid binding. There are two independent Sso10b2 proteins in the asymmetric unit, and a plausible stable dimer could be deduced from the crystal structure. Topology comparison revealed that Sso10b2 is similar to several RNA-binding proteins, including IF3-C, YhhP, and DNase I. Models of the Sso10b2 dimer bound to either B-DNA or A-DNA have been constructed.
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{{ABSTRACT_PUBMED_12837780}}
==About this Structure==
==About this Structure==
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[[Category: Wang, A H.J.]]
[[Category: Wang, A H.J.]]
[[Category: Dna binding protein]]
[[Category: Dna binding protein]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Jul 28 23:54:36 2008''

Revision as of 20:54, 28 July 2008

Image:1udv.png

Template:STRUCTURE 1udv

Crystal structure of the hyperthermophilic archaeal dna-binding protein Sso10b2 at 1.85 A

Template:ABSTRACT PUBMED 12837780

About this Structure

1UDV is a Single protein structure of sequence from Sulfolobus solfataricus. Full crystallographic information is available from OCA.

Reference

Crystal structure of the hyperthermophilic archaeal DNA-binding protein Sso10b2 at a resolution of 1.85 Angstroms., Chou CC, Lin TW, Chen CY, Wang AH, J Bacteriol. 2003 Jul;185(14):4066-73. PMID:12837780

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