1pdg

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{{STRUCTURE_1pdg| PDB=1pdg | SCENE= }}
{{STRUCTURE_1pdg| PDB=1pdg | SCENE= }}
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'''CRYSTAL STRUCTURE OF HUMAN PLATELET-DERIVED GROWTH FACTOR BB'''
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===CRYSTAL STRUCTURE OF HUMAN PLATELET-DERIVED GROWTH FACTOR BB===
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==Overview==
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The crystal structure of the homodimeric BB isoform of human recombinant platelet-derived growth factor (PDGF-BB) has been determined by X-ray analysis to 3.0 A resolution. The polypeptide chain is folded into two highly twisted antiparallel pairs of beta-strands and contains an unusual knotted arrangement of three intramolecular disulfide bonds. Dimerization leads to the clustering of three surface loops at each end of the elongated dimer, which most probably form the receptor recognition sites.
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(as it appears on PubMed at http://www.pubmed.gov), where 1396586 is the PubMed ID number.
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{{ABSTRACT_PUBMED_1396586}}
==About this Structure==
==About this Structure==
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[[Category: Winkler, F K.]]
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[[Category: Growth factor]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul 29 00:00:53 2008''

Revision as of 21:00, 28 July 2008

Image:1pdg.png

Template:STRUCTURE 1pdg

CRYSTAL STRUCTURE OF HUMAN PLATELET-DERIVED GROWTH FACTOR BB

Template:ABSTRACT PUBMED 1396586

About this Structure

1PDG is a Single protein structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

Crystal structure of human platelet-derived growth factor BB., Oefner C, D'Arcy A, Winkler FK, Eggimann B, Hosang M, EMBO J. 1992 Nov;11(11):3921-6. PMID:1396586

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