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1zta

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[[Image:1zta.gif|left|200px]]
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{{STRUCTURE_1zta| PDB=1zta | SCENE= }}
{{STRUCTURE_1zta| PDB=1zta | SCENE= }}
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'''THE SOLUTION STRUCTURE OF A LEUCINE-ZIPPER MOTIF PEPTIDE'''
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===THE SOLUTION STRUCTURE OF A LEUCINE-ZIPPER MOTIF PEPTIDE===
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==Overview==
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We report the complete structure determination of a 34 residue synthetic peptide with the amino acid sequence of the dimerization domain (leucine zipper) of GCN4. A high resolution structure in solution was obtained by 1H-NMR studies and distance geometry calculations followed by restrained energy minimization. A set of 20 final structures was obtained with an average root mean square deviation of 1.3 A for the backbone atoms (excluding the first and the last two residues). The structure contains an uninterrupted helix. A comparison with a structure previously determined for a larger peptide containing both the DNA-binding region (basic region) and the leucine-zipper motif shows the structural independence of the leucine-zipper domain from the contiguous DNA binding region.
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(as it appears on PubMed at http://www.pubmed.gov), where 1891459 is the PubMed ID number.
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{{ABSTRACT_PUBMED_1891459}}
==About this Structure==
==About this Structure==
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1ZTA is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1ZTA OCA].
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1ZTA is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1ZTA OCA].
==Reference==
==Reference==
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[[Category: Saudek, V.]]
[[Category: Saudek, V.]]
[[Category: Dna-binding motif]]
[[Category: Dna-binding motif]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sat May 3 18:02:39 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul 29 00:39:30 2008''

Revision as of 21:39, 28 July 2008

Image:1zta.png

Template:STRUCTURE 1zta

THE SOLUTION STRUCTURE OF A LEUCINE-ZIPPER MOTIF PEPTIDE

Template:ABSTRACT PUBMED 1891459

About this Structure

1ZTA is a Single protein structure of sequence from Saccharomyces cerevisiae. Full experimental information is available from OCA.

Reference

The solution structure of a leucine-zipper motif peptide., Saudek V, Pastore A, Morelli MA, Frank R, Gausepohl H, Gibson T, Protein Eng. 1991 Jun;4(5):519-29. PMID:1891459

Page seeded by OCA on Tue Jul 29 00:39:30 2008

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