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1vrq

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[[Image:1vrq.gif|left|200px]]
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{{STRUCTURE_1vrq| PDB=1vrq | SCENE= }}
{{STRUCTURE_1vrq| PDB=1vrq | SCENE= }}
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'''Crystal Structure of Heterotetrameric Sarcosine Oxidase from Corynebacterium sp. U-96 in complex with Folinic Acid'''
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===Crystal Structure of Heterotetrameric Sarcosine Oxidase from Corynebacterium sp. U-96 in complex with Folinic Acid===
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==Overview==
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Sarcosine oxidase from Corynebacterium sp. U-96 is a heterotetrameric enzyme. Here we report the crystal structures of the enzyme in complex with dimethylglycine and folinic acid. The alpha subunit is composed of two domains, contains NAD(+), and binds folinic acid. The beta subunit contains dimethylglycine, FAD, and FMN, and these flavins are approximately 10A apart. The gamma subunit is in contact with two domains of alpha subunit and has possibly a folate-binding structure. The delta subunit contains a single atom of zinc and has a Cys(3)His zinc finger structure. Based on the structures determined and on the previous works, the structure-function relationship on the heterotetrameric sarcosine oxidase is discussed.
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(as it appears on PubMed at http://www.pubmed.gov), where 15946648 is the PubMed ID number.
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{{ABSTRACT_PUBMED_15946648}}
==About this Structure==
==About this Structure==
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[[Category: Flavoenzyme]]
[[Category: Flavoenzyme]]
[[Category: Heterotetrameric sarcosine oxidase]]
[[Category: Heterotetrameric sarcosine oxidase]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sat May 3 12:50:38 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul 29 00:42:25 2008''

Revision as of 21:42, 28 July 2008

Image:1vrq.png

Template:STRUCTURE 1vrq

Crystal Structure of Heterotetrameric Sarcosine Oxidase from Corynebacterium sp. U-96 in complex with Folinic Acid

Template:ABSTRACT PUBMED 15946648

About this Structure

1VRQ is a Protein complex structure of sequences from Corynebacterium sp.. Full crystallographic information is available from OCA.

Reference

Crystal structure of heterotetrameric sarcosine oxidase from Corynebacterium sp. U-96., Ida K, Moriguchi T, Suzuki H, Biochem Biophys Res Commun. 2005 Jul 29;333(2):359-66. PMID:15946648

Page seeded by OCA on Tue Jul 29 00:42:25 2008

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