1p90

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{{STRUCTURE_1p90| PDB=1p90 | SCENE= }}
{{STRUCTURE_1p90| PDB=1p90 | SCENE= }}
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'''The Three-dimensional Structure of the Core Domain of NafY from Azotobacter vinelandii determined at 1.8 resolution'''
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===The Three-dimensional Structure of the Core Domain of NafY from Azotobacter vinelandii determined at 1.8 resolution===
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==Overview==
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The Azotobacter vinelandii NafY protein (nitrogenase accessory factor Y) is able to bind either to the iron molybdenum cofactor (FeMo-co) or to apodinitrogenase and is believed to facilitate the transfer of FeMo-co into apodinitrogenase. The NafY protein has two domains: an N-terminal domain (residues Met1-Leu98) and a C-terminal domain (residues Glu99-Ser232), referred here to as the "core domain." The core domain of NafY is shown here to be capable of binding the FeMo cofactor of nitrogenase but unable to bind to apodinitrogenase in the absence of the first domain. The three-dimensional molecular structure of the core domain of NafY has been solved to 1.8-A resolution, revealing that the protein consists of a mixed five-stranded beta-sheet flanked by five alpha-helices that belongs to the ribonuclease H superfamily. As such, this represents a new fold capable of binding FeMo-co, where the only previous example was that seen in dinitrogenase.
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{{ABSTRACT_PUBMED_12754195}}
==About this Structure==
==About this Structure==
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[[Category: Thoden, J B.]]
[[Category: Thoden, J B.]]
[[Category: Ribonuclease h motif]]
[[Category: Ribonuclease h motif]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sat May 3 04:50:07 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul 29 00:47:35 2008''

Revision as of 21:47, 28 July 2008

Image:1p90.png

Template:STRUCTURE 1p90

The Three-dimensional Structure of the Core Domain of NafY from Azotobacter vinelandii determined at 1.8 resolution

Template:ABSTRACT PUBMED 12754195

About this Structure

1P90 is a Single protein structure of sequence from Azotobacter vinelandii. Full crystallographic information is available from OCA.

Reference

The three-dimensional structure of the core domain of Naf Y from Azotobacter vinelandii determined at 1.8-A resolution., Dyer DH, Rubio LM, Thoden JB, Holden HM, Ludden PW, Rayment I, J Biol Chem. 2003 Aug 22;278(34):32150-6. Epub 2003 May 16. PMID:12754195

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