1uw7

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Line 1: Line 1:
-
[[Image:1uw7.gif|left|200px]]
+
{{Seed}}
 +
[[Image:1uw7.png|left|200px]]
<!--
<!--
Line 9: Line 10:
{{STRUCTURE_1uw7| PDB=1uw7 | SCENE= }}
{{STRUCTURE_1uw7| PDB=1uw7 | SCENE= }}
-
'''NSP9 PROTEIN FROM SARS-CORONAVIRUS.'''
+
===NSP9 PROTEIN FROM SARS-CORONAVIRUS.===
-
==Overview==
+
<!--
-
As part of a high-throughput structural analysis of SARS-coronavirus (SARS-CoV) proteins, we have solved the structure of the non-structural protein 9 (nsp9). This protein, encoded by ORF1a, has no designated function but is most likely involved with viral RNA synthesis. The protein comprises a single beta-barrel with a fold previously unseen in single domain proteins. The fold superficially resembles an OB-fold with a C-terminal extension and is related to both of the two subdomains of the SARS-CoV 3C-like protease (which belongs to the serine protease superfamily). nsp9 has, presumably, evolved from a protease. The crystal structure suggests that the protein is dimeric. This is confirmed by analytical ultracentrifugation and dynamic light scattering. We show that nsp9 binds RNA and interacts with nsp8, activities that may be essential for its function(s).
+
The line below this paragraph, {{ABSTRACT_PUBMED_14962394}}, adds the Publication Abstract to the page
 +
(as it appears on PubMed at http://www.pubmed.gov), where 14962394 is the PubMed ID number.
 +
-->
 +
{{ABSTRACT_PUBMED_14962394}}
==About this Structure==
==About this Structure==
Line 45: Line 49:
[[Category: Viral protein]]
[[Category: Viral protein]]
[[Category: Virus]]
[[Category: Virus]]
-
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sat May 3 11:45:53 2008''
+
 
 +
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul 29 02:10:20 2008''

Revision as of 23:10, 28 July 2008

Image:1uw7.png

Template:STRUCTURE 1uw7

NSP9 PROTEIN FROM SARS-CORONAVIRUS.

Template:ABSTRACT PUBMED 14962394

About this Structure

1UW7 is a Single protein structure of sequence from Viruses. Full crystallographic information is available from OCA.

Reference

The nsp9 replicase protein of SARS-coronavirus, structure and functional insights., Sutton G, Fry E, Carter L, Sainsbury S, Walter T, Nettleship J, Berrow N, Owens R, Gilbert R, Davidson A, Siddell S, Poon LL, Diprose J, Alderton D, Walsh M, Grimes JM, Stuart DI, Structure. 2004 Feb;12(2):341-53. PMID:14962394

Page seeded by OCA on Tue Jul 29 02:10:20 2008

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/1uw7"
Personal tools