2z8x

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{{STRUCTURE_2z8x| PDB=2z8x | SCENE= }}
{{STRUCTURE_2z8x| PDB=2z8x | SCENE= }}
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'''Crystal structure of extracellular lipase from Pseudomonas sp. MIS38'''
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===Crystal structure of extracellular lipase from Pseudomonas sp. MIS38===
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==Overview==
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The crystal structure of a family I.3 lipase from Pseudomonas sp. MIS38 in a closed conformation was determined at 1.5A resolution. This structure highly resembles that of Serratia marcescens LipA in an open conformation, except for the structures of two lids. Lid1 is anchored by a Ca2+ ion (Ca1) in an open conformation, but lacks this Ca1 site and greatly changes its structure and position in a closed conformation. Lid2 forms a helical hairpin in an open conformation, but does not form it and covers the active site in a closed conformation. Based on these results, we discuss on the lid-opening mechanism.
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(as it appears on PubMed at http://www.pubmed.gov), where 17923123 is the PubMed ID number.
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{{ABSTRACT_PUBMED_17923123}}
==About this Structure==
==About this Structure==
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[[Category: Hydrolase]]
[[Category: Hydrolase]]
[[Category: Rtx protein]]
[[Category: Rtx protein]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun May 4 20:03:10 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul 29 02:30:20 2008''

Revision as of 23:30, 28 July 2008

Template:STRUCTURE 2z8x

Crystal structure of extracellular lipase from Pseudomonas sp. MIS38

Template:ABSTRACT PUBMED 17923123

About this Structure

2Z8X is a Single protein structure of sequence from Pseudomonas sp. mis38. Full crystallographic information is available from OCA.

Reference

Crystal structure of a family I.3 lipase from Pseudomonas sp. MIS38 in a closed conformation., Angkawidjaja C, You DJ, Matsumura H, Kuwahara K, Koga Y, Takano K, Kanaya S, FEBS Lett. 2007 Oct 30;581(26):5060-4. Epub 2007 Oct 1. PMID:17923123

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