1t4v
From Proteopedia
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{{STRUCTURE_1t4v| PDB=1t4v | SCENE= }} | {{STRUCTURE_1t4v| PDB=1t4v | SCENE= }} | ||
| - | + | ===Crystal Structure Analysis of a novel Oxyguanidine bound to Thrombin=== | |
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==Disease== | ==Disease== | ||
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[[Category: Spurlino, J.]] | [[Category: Spurlino, J.]] | ||
[[Category: Hydrolase]] | [[Category: Hydrolase]] | ||
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Revision as of 23:36, 28 July 2008
Contents |
Crystal Structure Analysis of a novel Oxyguanidine bound to Thrombin
Template:ABSTRACT PUBMED 15203151
Disease
Known disease associated with this structure: Dysprothrombinemia OMIM:[176930], Hyperprothrombinemia OMIM:[176930], Hypoprothrombinemia OMIM:[176930]
About this Structure
1T4V is a Protein complex structure of sequences from Hirudo medicinalis and Homo sapiens. Full crystallographic information is available from OCA.
Reference
Oxyguanidines. Part 2: Discovery of a novel orally active thrombin inhibitor through structure-based drug design and parallel synthesis., Lu T, Markotan T, Coppo F, Tomczuk B, Crysler C, Eisennagel S, Spurlino J, Gremminger L, Soll RM, Giardino EC, Bone R, Bioorg Med Chem Lett. 2004 Jul 16;14(14):3727-31. PMID:15203151
Page seeded by OCA on Tue Jul 29 02:36:24 2008
