2qu4

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{{STRUCTURE_2qu4| PDB=2qu4 | SCENE= }}
{{STRUCTURE_2qu4| PDB=2qu4 | SCENE= }}
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'''Model for Bacterial ParM Filament'''
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===Model for Bacterial ParM Filament===
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==Overview==
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Bacterial ParM is a homolog of eukaryotic actin and is involved in moving plasmids so that they segregate properly during cell division. Using cryo-EM and three-dimensional reconstruction, we show that ParM filaments have a different structure from F-actin, with very different subunit-subunit interfaces. These interfaces result in the helical handedness of the ParM filament being opposite to that of F-actin. Like F-actin, ParM filaments have a variable twist, and we show that this involves domain-domain rotations within the ParM subunit. The present results yield new insights into polymorphisms within F-actin, as well as the evolution of polymer families.
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(as it appears on PubMed at http://www.pubmed.gov), where 17873883 is the PubMed ID number.
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{{ABSTRACT_PUBMED_17873883}}
==About this Structure==
==About this Structure==
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[[Category: Plasmid partition]]
[[Category: Plasmid partition]]
[[Category: Structural protein]]
[[Category: Structural protein]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun May 4 15:41:01 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul 29 03:05:42 2008''

Revision as of 00:05, 29 July 2008

Image:2qu4.png

Template:STRUCTURE 2qu4

Model for Bacterial ParM Filament

Template:ABSTRACT PUBMED 17873883

About this Structure

2QU4 is a Single protein structure of sequence from Escherichia coli. Full crystallographic information is available from OCA.

Reference

The structure of bacterial ParM filaments., Orlova A, Garner EC, Galkin VE, Heuser J, Mullins RD, Egelman EH, Nat Struct Mol Biol. 2007 Oct;14(10):921-6. Epub 2007 Sep 16. PMID:17873883

Page seeded by OCA on Tue Jul 29 03:05:42 2008

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