2a2t

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{{STRUCTURE_2a2t| PDB=2a2t | SCENE= }}
{{STRUCTURE_2a2t| PDB=2a2t | SCENE= }}
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'''crystal structure of d(AAATATTT)'''
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===crystal structure of d(AAATATTT)===
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==Overview==
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The structure of the oligonucleotide duplex d(AAATATTT)(2) has been obtained in two crystal forms. In both cases the duplexes show Watson-Crick base pairs and are organized as a helical arrangement of stacked oligonucleotides. The helices contain either 11 duplexes in seven turns (form I) or 14 duplexes in nine turns (form II). As a result, the crystals have rather large unit cells. Such an organization of DNA duplexes has not been previously described in oligonucleotide crystal structures. The columns of stacked duplexes are organized in a pseudohexagonal arrangement. They do not show any direct lateral interactions; instead, these are indirectly mediated by shared and disordered hydrated ions. Such interactions are similar to those found in DNA fibres. The structural parameters of the individual base steps coincide with those found in other structures which contain CG terminal base pairs.
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(as it appears on PubMed at http://www.pubmed.gov), where 16301792 is the PubMed ID number.
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{{ABSTRACT_PUBMED_16301792}}
==About this Structure==
==About this Structure==
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[[Category: Haso]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul 29 03:15:54 2008''

Revision as of 00:16, 29 July 2008

Image:2a2t.png

Template:STRUCTURE 2a2t

crystal structure of d(AAATATTT)

Template:ABSTRACT PUBMED 16301792

About this Structure

Full crystallographic information is available from OCA.

Reference

Structure of a DNA duplex with all-AT base pairs., Valls N, Richter M, Subirana JA, Acta Crystallogr D Biol Crystallogr. 2005 Dec;61(Pt 12):1587-93. Epub 2005, Nov 19. PMID:16301792

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