1oqv

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Line 1: Line 1:
-
[[Image:1oqv.jpg|left|200px]]
+
{{Seed}}
 +
[[Image:1oqv.png|left|200px]]
<!--
<!--
Line 9: Line 10:
{{STRUCTURE_1oqv| PDB=1oqv | SCENE= }}
{{STRUCTURE_1oqv| PDB=1oqv | SCENE= }}
-
'''Structure of TcpA, the Type IV pilin subunit from the toxin co-regulated pilus of Vibrio cholerae classical biotype'''
+
===Structure of TcpA, the Type IV pilin subunit from the toxin co-regulated pilus of Vibrio cholerae classical biotype===
-
==Overview==
+
<!--
-
Pilin assembly into type IV pili is required for virulence by bacterial pathogens that cause diseases such as cholera, pneumonia, gonorrhea, and meningitis. Crystal structures of soluble, N-terminally truncated pilin from Vibrio cholera toxin-coregulated pilus (TCP) and full-length PAK pilin from Pseudomonas aeruginosa reveal a novel TCP fold, yet a shared architecture for the type IV pilins. In each pilin subunit a conserved, extended, N-terminal alpha helix wrapped by beta strands anchors the structurally variable globular head. Inside the assembled pilus, characterized by cryo-electron microscopy and crystallography, the extended hydrophobic alpha helices make multisubunit contacts to provide mechanical strength and flexibility. Outside, distinct interactions of adaptable heads contribute surface variation for specificity of pilus function in antigenicity, motility, adhesion, and colony formation.
+
The line below this paragraph, {{ABSTRACT_PUBMED_12769840}}, adds the Publication Abstract to the page
 +
(as it appears on PubMed at http://www.pubmed.gov), where 12769840 is the PubMed ID number.
 +
-->
 +
{{ABSTRACT_PUBMED_12769840}}
==About this Structure==
==About this Structure==
Line 32: Line 36:
[[Category: Type iv pilin]]
[[Category: Type iv pilin]]
[[Category: Vibrio cholerae]]
[[Category: Vibrio cholerae]]
-
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sat May 3 04:10:24 2008''
+
 
 +
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul 29 03:25:32 2008''

Revision as of 00:25, 29 July 2008

Image:1oqv.png

Template:STRUCTURE 1oqv

Structure of TcpA, the Type IV pilin subunit from the toxin co-regulated pilus of Vibrio cholerae classical biotype

Template:ABSTRACT PUBMED 12769840

About this Structure

1OQV is a Single protein structure of sequence from Vibrio cholerae. Full crystallographic information is available from OCA.

Reference

Type IV pilin structure and assembly: X-ray and EM analyses of Vibrio cholerae toxin-coregulated pilus and Pseudomonas aeruginosa PAK pilin., Craig L, Taylor RK, Pique ME, Adair BD, Arvai AS, Singh M, Lloyd SJ, Shin DS, Getzoff ED, Yeager M, Forest KT, Tainer JA, Mol Cell. 2003 May;11(5):1139-50. PMID:12769840

Page seeded by OCA on Tue Jul 29 03:25:32 2008

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/1oqv"
Personal tools