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2gx9

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[[Image:2gx9.gif|left|200px]]
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{{STRUCTURE_2gx9| PDB=2gx9 | SCENE= }}
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'''X-ray strucutre of influenza virus NS1 effector domain'''
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===X-ray strucutre of influenza virus NS1 effector domain===
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==Overview==
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The nonstructural protein NS1 of influenza virus is an antagonist of host immune responses and is implicated in virulence. It has two domains, an N-terminal double-stranded RNA-binding domain (RBD) and an effector domain crucial for RBD function, for nuclear export and for sequestering messenger RNA-processing proteins. Here we present the crystallographic structure of the effector domain, which has a novel fold and suggests mechanisms for increased virulence in H5N1 strains.
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(as it appears on PubMed at http://www.pubmed.gov), where 16715094 is the PubMed ID number.
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{{ABSTRACT_PUBMED_16715094}}
==About this Structure==
==About this Structure==
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[[Category: Influenza]]
[[Category: Influenza]]
[[Category: Ns1]]
[[Category: Ns1]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun May 4 05:38:36 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul 29 03:27:39 2008''

Revision as of 00:27, 29 July 2008

Image:2gx9.png

Template:STRUCTURE 2gx9

X-ray strucutre of influenza virus NS1 effector domain

Template:ABSTRACT PUBMED 16715094

About this Structure

2GX9 is a Single protein structure of sequence from Unidentified influenza virus. Full crystallographic information is available from OCA.

Reference

X-ray structure of influenza virus NS1 effector domain., Bornholdt ZA, Prasad BV, Nat Struct Mol Biol. 2006 Jun;13(6):559-60. Epub 2006 May 21. PMID:16715094

Page seeded by OCA on Tue Jul 29 03:27:39 2008

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