1n7b

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{{Seed}}
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{{STRUCTURE_1n7b| PDB=1n7b | SCENE= }}
{{STRUCTURE_1n7b| PDB=1n7b | SCENE= }}
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'''RIP-Radiation-damage Induced Phasing'''
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===RIP-Radiation-damage Induced Phasing===
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==Overview==
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The use of third generation synchrotron sources has led to renewed concern about the effect of ionizing radiation on crystalline biological samples. In general, the problem is seen as one to be avoided. However, in this paper, it is shown that, far from being a hindrance to successful structure determination, radiation damage provides an opportunity for phasing macromolecular structures. This is successfully demonstrated for both a protein and an oligonucleotide, by way of which complete models were built automatically. The possibility that, through the exploitation of radiation damage, the phase problem could become less of a barrier to macromolecular crystal structure determination is discussed.
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The line below this paragraph, {{ABSTRACT_PUBMED_12575941}}, adds the Publication Abstract to the page
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(as it appears on PubMed at http://www.pubmed.gov), where 12575941 is the PubMed ID number.
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{{ABSTRACT_PUBMED_12575941}}
==About this Structure==
==About this Structure==
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sat May 3 02:11:01 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul 29 03:32:03 2008''

Revision as of 00:32, 29 July 2008

Image:1n7b.png

Template:STRUCTURE 1n7b

RIP-Radiation-damage Induced Phasing

Template:ABSTRACT PUBMED 12575941

About this Structure

Full crystallographic information is available from OCA.

Reference

Specific radiation damage can be used to solve macromolecular crystal structures., Ravelli RB, Leiros HK, Pan B, Caffrey M, McSweeney S, Structure. 2003 Feb;11(2):217-24. PMID:12575941

Page seeded by OCA on Tue Jul 29 03:32:03 2008

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