1pv4

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Line 1: Line 1:
-
[[Image:1pv4.gif|left|200px]]
+
{{Seed}}
 +
[[Image:1pv4.png|left|200px]]
<!--
<!--
Line 9: Line 10:
{{STRUCTURE_1pv4| PDB=1pv4 | SCENE= }}
{{STRUCTURE_1pv4| PDB=1pv4 | SCENE= }}
-
'''X-ray crystal structure of the Rho transcription termination factor in complex with single stranded DNA'''
+
===X-ray crystal structure of the Rho transcription termination factor in complex with single stranded DNA===
-
==Overview==
+
<!--
-
In bacteria, one of the major transcriptional termination mechanisms requires a RNA/DNA helicase known as the Rho factor. We have determined two structures of Rho complexed with nucleic acid recognition site mimics in both free and nucleotide bound states to 3.0 A resolution. Both structures show that Rho forms a hexameric ring in which two RNA binding sites--a primary one responsible for target mRNA recognition and a secondary one required for mRNA translocation and unwinding--point toward the center of the ring. Rather than forming a closed ring, the Rho hexamer is split open, resembling a "lock washer" in its global architecture. The distance between subunits at the opening is sufficiently wide (12 A) to accommodate single-stranded RNA. This open configuration most likely resembles a state poised to load onto mRNA and suggests how related ring-shaped enzymes may be breached to bind nucleic acids.
+
The line below this paragraph, {{ABSTRACT_PUBMED_12859904}}, adds the Publication Abstract to the page
 +
(as it appears on PubMed at http://www.pubmed.gov), where 12859904 is the PubMed ID number.
 +
-->
 +
{{ABSTRACT_PUBMED_12859904}}
==About this Structure==
==About this Structure==
Line 25: Line 29:
[[Category: Skordalakes, E.]]
[[Category: Skordalakes, E.]]
[[Category: Protein-ssdna complex]]
[[Category: Protein-ssdna complex]]
-
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Apr 30 13:55:31 2008''
+
 
 +
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul 29 04:40:16 2008''

Revision as of 01:40, 29 July 2008

Image:1pv4.png

Template:STRUCTURE 1pv4

X-ray crystal structure of the Rho transcription termination factor in complex with single stranded DNA

Template:ABSTRACT PUBMED 12859904

About this Structure

1PV4 is a Single protein structure of sequence from Escherichia coli. Full crystallographic information is available from OCA.

Reference

Structure of the Rho transcription terminator: mechanism of mRNA recognition and helicase loading., Skordalakes E, Berger JM, Cell. 2003 Jul 11;114(1):135-46. PMID:12859904

Page seeded by OCA on Tue Jul 29 04:40:16 2008

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/1pv4"
Personal tools