238d

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{{Seed}}
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{{STRUCTURE_238d| PDB=238d | SCENE= }}
{{STRUCTURE_238d| PDB=238d | SCENE= }}
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'''CRYSTAL STRUCTURE OF THE DNA DECAMER D(AGG(BR)CATGCCT): COMPARISON WITH D(AGGCATGCCT) AND IMPLICATIONS FOR COBALT HEXAMMINE BINDING TO DNA'''
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===CRYSTAL STRUCTURE OF THE DNA DECAMER D(AGG(BR)CATGCCT): COMPARISON WITH D(AGGCATGCCT) AND IMPLICATIONS FOR COBALT HEXAMMINE BINDING TO DNA===
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==Overview==
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The crystal structure of the DNA decamer d(AGGBrCATGCCT) has been determined to a resolution of 2.0 A and R factor of 19.6%. Crystals of d(AGGBrCATGCCT) were grown in the presence of cobalt hexammine but no cobalt hexammine ions are bound to the DNA structure. This contrasts with the recently determined crystal structure of d(AGGCATGCCT) which has a similar DNA conformation and cobalt hexammine ions bound directly to the DNA. Comparison with the structure of d(AGGCATGCCT) and appreciation of the crystal packing of this sequence leads to an understanding of how cobalt hexammine binding to DNA occurs and its role in determining DNA conformation.
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The line below this paragraph, {{ABSTRACT_PUBMED_8877561}}, adds the Publication Abstract to the page
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(as it appears on PubMed at http://www.pubmed.gov), where 8877561 is the PubMed ID number.
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{{ABSTRACT_PUBMED_8877561}}
==About this Structure==
==About this Structure==
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[[Category: Double helix]]
[[Category: Double helix]]
[[Category: Flipped-out base]]
[[Category: Flipped-out base]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sat May 3 18:21:49 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul 29 04:45:15 2008''

Revision as of 01:45, 29 July 2008

Image:238d.png

Template:STRUCTURE 238d

CRYSTAL STRUCTURE OF THE DNA DECAMER D(AGG(BR)CATGCCT): COMPARISON WITH D(AGGCATGCCT) AND IMPLICATIONS FOR COBALT HEXAMMINE BINDING TO DNA

Template:ABSTRACT PUBMED 8877561

About this Structure

Full crystallographic information is available from OCA.

Reference

Crystal structure of d(AGGBrCATGCCT): implications for cobalt hexammine binding to DNA., Nunn CM, J Biomol Struct Dyn. 1996 Aug;14(1):49-55. PMID:8877561

Page seeded by OCA on Tue Jul 29 04:45:15 2008

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