1o56

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Line 1: Line 1:
-
[[Image:1o56.gif|left|200px]]
+
{{Seed}}
 +
[[Image:1o56.png|left|200px]]
<!--
<!--
Line 9: Line 10:
{{STRUCTURE_1o56| PDB=1o56 | SCENE= }}
{{STRUCTURE_1o56| PDB=1o56 | SCENE= }}
-
'''MOLECULAR STRUCTURE OF TWO CRYSTAL FORMS OF CYCLIC TRIADENYLIC ACID AT 1 ANGSTROM RESOLUTION'''
+
===MOLECULAR STRUCTURE OF TWO CRYSTAL FORMS OF CYCLIC TRIADENYLIC ACID AT 1 ANGSTROM RESOLUTION===
-
==Overview==
+
<!--
-
The three dimensional structures of cyclic deoxytriadenylic acid, c-d(ApApAp), from two different trigonal crystal forms (space groups P3 and R32) have been determined by x-ray diffraction analysis at 1A resolution. Both structures were solved by direct methods and refined by anisotropic least squares refinement to R-factors of 0.109 and 0.137 for the P3 and R32 forms, respectively. In both crystal forms, each of the two independent c-d(ApApAp) molecules sits on the crystallographic 3-fold axis. All four independent c-d(ApApAp) molecules have similar backbone conformations. The deoxyriboses are in the S-type pucker with pseudorotation angles ranging from 156.7 degrees to 168.6 degrees and the bases have anti glycosyl torsion angles (chi falling in two ranges, one at -104.3 degrees and the other ranging from -141.0 degrees to -143.8 degrees). In the R32 form, a hexahydrated cobalt(II) ion is found to coordinate through bridging water molecules to N1, N3, and N7 atoms of three adjacent adenines and oxygen atoms of phosphates. Comparison with other structures of cyclic oligonucleotides indicates that the sugar adopts N-type pucker in cyclic dinucleotides and S-type pucker in cyclic trinucleotides, regardless whether the sugar is a ribose or a deoxyribose.
+
The line below this paragraph, {{ABSTRACT_PUBMED_9745896}}, adds the Publication Abstract to the page
 +
(as it appears on PubMed at http://www.pubmed.gov), where 9745896 is the PubMed ID number.
 +
-->
 +
{{ABSTRACT_PUBMED_9745896}}
==About this Structure==
==About this Structure==
Line 28: Line 32:
[[Category: Wang, A H.]]
[[Category: Wang, A H.]]
[[Category: Cyclic trinucleotide]]
[[Category: Cyclic trinucleotide]]
-
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sat May 3 03:23:54 2008''
+
 
 +
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul 29 04:51:18 2008''

Revision as of 01:51, 29 July 2008

Image:1o56.png

Template:STRUCTURE 1o56

MOLECULAR STRUCTURE OF TWO CRYSTAL FORMS OF CYCLIC TRIADENYLIC ACID AT 1 ANGSTROM RESOLUTION

Template:ABSTRACT PUBMED 9745896

About this Structure

This structure supersedes the now removed PDB entry 416d. Full crystallographic information is available from OCA.

Reference

Molecular structure of two crystal forms of cyclic triadenylic acid at 1A resolution., Gao YG, Robinson H, Guan Y, Liaw YC, van Boom JH, van der Marel GA, Wang AH, J Biomol Struct Dyn. 1998 Aug;16(1):69-76. PMID:9745896

Page seeded by OCA on Tue Jul 29 04:51:18 2008

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/1o56"
Personal tools