1q3i

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{{STRUCTURE_1q3i| PDB=1q3i | SCENE= }}
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'''Crystal Structure of Na,K-ATPase N-domain'''
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===Crystal Structure of Na,K-ATPase N-domain===
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==Overview==
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The structure of the N-domain of porcine alpha(2) Na,K-ATPase was determined crystallographically to 3.2A resolution by isomorphous heavy-atom replacement using a single mercury derivative. The structure was finally refined against 2.6A resolution synchrotron data. The domain forms a seven-stranded antiparallel beta-sheet with two additional beta-strands forming a hairpin and five alpha-helices. Approximately 75% of the residues were superimposable with residues from the structure of Ca-ATPase N-domain, and a structure-based sequence alignment is presented. The positions of key residues are discussed in relation to the pattern of hydrophobicity, charge and sequence conservation of the molecular surface. The structure of a hexahistidine tag binding to nickel ions is presented.
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(as it appears on PubMed at http://www.pubmed.gov), where 14499619 is the PubMed ID number.
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{{ABSTRACT_PUBMED_14499619}}
==About this Structure==
==About this Structure==
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[[Category: Hakansson, K O.]]
[[Category: Hakansson, K O.]]
[[Category: Anti-parallel beta sheet]]
[[Category: Anti-parallel beta sheet]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul 29 05:09:59 2008''

Revision as of 02:10, 29 July 2008

Image:1q3i.png

Template:STRUCTURE 1q3i

Crystal Structure of Na,K-ATPase N-domain

Template:ABSTRACT PUBMED 14499619

About this Structure

Full crystallographic information is available from OCA.

Reference

The crystallographic structure of Na,K-ATPase N-domain at 2.6A resolution., Hakansson KO, J Mol Biol. 2003 Oct 3;332(5):1175-82. PMID:14499619

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