2bgd

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[[Image:2bgd.gif|left|200px]]
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{{Seed}}
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{{STRUCTURE_2bgd| PDB=2bgd | SCENE= }}
{{STRUCTURE_2bgd| PDB=2bgd | SCENE= }}
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'''STRUCTURE-BASED DESIGN OF PROTEIN TYROSINE PHOSPHATASE-1B INHIBITORS'''
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===STRUCTURE-BASED DESIGN OF PROTEIN TYROSINE PHOSPHATASE-1B INHIBITORS===
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==Overview==
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Using structure-based design, a new class of inhibitors of protein tyrosine phosphatase-1B (PTP1B) has been identified, which incorporate the 1,2,5-thiadiazolidin-3-one-1,1-dioxide template.
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The line below this paragraph, {{ABSTRACT_PUBMED_15863305}}, adds the Publication Abstract to the page
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(as it appears on PubMed at http://www.pubmed.gov), where 15863305 is the PubMed ID number.
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{{ABSTRACT_PUBMED_15863305}}
==About this Structure==
==About this Structure==
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[[Category: Hydrolase]]
[[Category: Hydrolase]]
[[Category: Protein tyrosine phosphatase]]
[[Category: Protein tyrosine phosphatase]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sat May 3 20:14:52 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul 29 05:41:11 2008''

Revision as of 02:41, 29 July 2008

Image:2bgd.png

Template:STRUCTURE 2bgd

STRUCTURE-BASED DESIGN OF PROTEIN TYROSINE PHOSPHATASE-1B INHIBITORS

Template:ABSTRACT PUBMED 15863305

About this Structure

2BGD is a Single protein structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

Structure-based design of protein tyrosine phosphatase-1B inhibitors., Black E, Breed J, Breeze AL, Embrey K, Garcia R, Gero TW, Godfrey L, Kenny PW, Morley AD, Minshull CA, Pannifer AD, Read J, Rees A, Russell DJ, Toader D, Tucker J, Bioorg Med Chem Lett. 2005 May 16;15(10):2503-7. PMID:15863305

Page seeded by OCA on Tue Jul 29 05:41:11 2008

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