This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.

Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


1r94

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Line 1: Line 1:
-
[[Image:1r94.jpg|left|200px]]
+
{{Seed}}
 +
[[Image:1r94.png|left|200px]]
<!--
<!--
Line 9: Line 10:
{{STRUCTURE_1r94| PDB=1r94 | SCENE= }}
{{STRUCTURE_1r94| PDB=1r94 | SCENE= }}
-
'''Crystal Structure of IscA (MERCURY DERIVATIVE)'''
+
===Crystal Structure of IscA (MERCURY DERIVATIVE)===
-
==Overview==
+
<!--
-
IscA belongs to an ancient family of proteins responsible for iron-sulfur cluster assembly in essential metabolic pathways preserved throughout evolution. We report here the 2.3 A resolution crystal structure of Escherichia coli IscA, a novel fold in which mixed beta-sheets form a compact alpha-beta sandwich domain. In contrast to the highly mobile secondary structural elements within the bacterial Fe-S scaffold protein IscU, a protein which is thought to have a similar function, the great majority of the amino acids that are conserved in IscA homologues are located in elements that constitute a well-ordered fold. However, the 10-residue C-terminal tail segment that contains two invariant cysteines critical for the Fe-S-binding function of a cyanobacterial (Synechocystis PCC) IscA homologue is not ordered in our structure. In addition, the crystal packing reveals a helical assembly that is constructed from two possible tetrameric oligomers of IscA.
+
The line below this paragraph, {{ABSTRACT_PUBMED_14705938}}, adds the Publication Abstract to the page
 +
(as it appears on PubMed at http://www.pubmed.gov), where 14705938 is the PubMed ID number.
 +
-->
 +
{{ABSTRACT_PUBMED_14705938}}
==About this Structure==
==About this Structure==
Line 29: Line 33:
[[Category: Pseudo-symmetric motif]]
[[Category: Pseudo-symmetric motif]]
[[Category: Tetrameric]]
[[Category: Tetrameric]]
-
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sat May 3 07:13:59 2008''
+
 
 +
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul 29 05:41:41 2008''

Revision as of 02:41, 29 July 2008

Image:1r94.png

Template:STRUCTURE 1r94

Crystal Structure of IscA (MERCURY DERIVATIVE)

Template:ABSTRACT PUBMED 14705938

About this Structure

1R94 is a Single protein structure of sequence from Escherichia coli. Full crystallographic information is available from OCA.

Reference

Crystal structure of the ancient, Fe-S scaffold IscA reveals a novel protein fold., Bilder PW, Ding H, Newcomer ME, Biochemistry. 2004 Jan 13;43(1):133-9. PMID:14705938

Page seeded by OCA on Tue Jul 29 05:41:41 2008

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/1r94"
Personal tools