2avu

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Line 1: Line 1:
-
[[Image:2avu.gif|left|200px]]
+
{{Seed}}
 +
[[Image:2avu.png|left|200px]]
<!--
<!--
Line 9: Line 10:
{{STRUCTURE_2avu| PDB=2avu | SCENE= }}
{{STRUCTURE_2avu| PDB=2avu | SCENE= }}
-
'''Structure of the Escherichia coli FlhDC complex, a prokaryotic heteromeric regulator of transcription'''
+
===Structure of the Escherichia coli FlhDC complex, a prokaryotic heteromeric regulator of transcription===
-
==Overview==
+
<!--
-
The hetero-oligomeric complex of the FlhD and FlhC proteins (FlhDC) regulates transcription from several flagellar and non-flagellar operons in bacteria. The crystallographic structure of the Escherichia coli FlhDC complex has been solved to 3.0 A resolution, revealing a hexameric FlhD4FlhC2 assembly. In the complex, each FlhC protomer binds an FlhD2 dimer; the conformation of the dimer in the complex differs significantly from its conformation in the absence of FlhC. FlhC has a novel tertiary fold that includes a heretofore unrecognized zinc-binding site in which the ion is ligated by four cysteine residues. Gel shift experiments show that binding of the FlhDC complex to a cognate promoter bends the DNA by approximately 111 degrees . The structure of the FlhDC complex is compatible with models in which a fragment of operator DNA, at least 48 base-pairs in length, wraps around the complex and bends significantly when binding.
+
The line below this paragraph, {{ABSTRACT_PUBMED_16337229}}, adds the Publication Abstract to the page
 +
(as it appears on PubMed at http://www.pubmed.gov), where 16337229 is the PubMed ID number.
 +
-->
 +
{{ABSTRACT_PUBMED_16337229}}
==About this Structure==
==About this Structure==
Line 28: Line 32:
[[Category: Westbrook, E M.]]
[[Category: Westbrook, E M.]]
[[Category: C4-type zinc finger]]
[[Category: C4-type zinc finger]]
-
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sat May 3 19:31:59 2008''
+
 
 +
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul 29 06:14:01 2008''

Revision as of 03:14, 29 July 2008

Image:2avu.png

Template:STRUCTURE 2avu

Structure of the Escherichia coli FlhDC complex, a prokaryotic heteromeric regulator of transcription

Template:ABSTRACT PUBMED 16337229

About this Structure

2AVU is a Protein complex structure of sequences from Escherichia coli. Full crystallographic information is available from OCA.

Reference

Structure of the Escherichia coli FlhDC complex, a prokaryotic heteromeric regulator of transcription., Wang S, Fleming RT, Westbrook EM, Matsumura P, McKay DB, J Mol Biol. 2006 Jan 27;355(4):798-808. Epub 2005 Nov 22. PMID:16337229

Page seeded by OCA on Tue Jul 29 06:14:01 2008

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/2avu"
Personal tools