1zlr
From Proteopedia
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{{STRUCTURE_1zlr| PDB=1zlr | SCENE= }} | {{STRUCTURE_1zlr| PDB=1zlr | SCENE= }} | ||
| - | + | ===Factor XI catalytic domain complexed with 2-guanidino-1-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)ethyl nicotinate=== | |
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==Disease== | ==Disease== | ||
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[[Category: Covalent inhibitor]] | [[Category: Covalent inhibitor]] | ||
[[Category: Serine protease]] | [[Category: Serine protease]] | ||
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| + | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul 29 06:33:18 2008'' | ||
Revision as of 03:33, 29 July 2008
Contents |
Factor XI catalytic domain complexed with 2-guanidino-1-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)ethyl nicotinate
Template:ABSTRACT PUBMED 16876411
Disease
Known disease associated with this structure: Factor XI deficiency, autosomal dominant OMIM:[264900], Factor XI deficiency, autosomal recessive OMIM:[264900]
About this Structure
1ZLR is a Single protein structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.
Reference
Synthesis and in vitro biological evaluation of aryl boronic acids as potential inhibitors of factor XIa., Lazarova TI, Jin L, Rynkiewicz M, Gorga JC, Bibbins F, Meyers HV, Babine R, Strickler J, Bioorg Med Chem Lett. 2006 Oct 1;16(19):5022-7. Epub 2006 Jul 28. PMID:16876411
Page seeded by OCA on Tue Jul 29 06:33:18 2008
