2gic

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{{STRUCTURE_2gic| PDB=2gic | SCENE= }}
{{STRUCTURE_2gic| PDB=2gic | SCENE= }}
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'''Crystal Structure of a vesicular stomatitis virus nucleocapsid-RNA complex'''
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===Crystal Structure of a vesicular stomatitis virus nucleocapsid-RNA complex===
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==Overview==
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Vesicular stomatitis virus is a negative-stranded RNA virus. Its nucleoprotein (N) binds the viral genomic RNA and is involved in multiple functions including transcription, replication, and assembly. We have determined a 2.9 angstrom structure of a complex containing 10 molecules of the N protein and 90 bases of RNA. The RNA is tightly sequestered in a cavity at the interface between two lobes of the N protein. This serves to protect the RNA in the absence of polynucleotide synthesis. For the RNA to be accessed, some conformational change in the N protein should be necessary.
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(as it appears on PubMed at http://www.pubmed.gov), where 16778022 is the PubMed ID number.
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{{ABSTRACT_PUBMED_16778022}}
==About this Structure==
==About this Structure==
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[[Category: Nucleocapsid]]
[[Category: Nucleocapsid]]
[[Category: Protein-rna complex]]
[[Category: Protein-rna complex]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun May 4 05:08:24 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul 29 07:01:50 2008''

Revision as of 04:01, 29 July 2008

Image:2gic.png

Template:STRUCTURE 2gic

Crystal Structure of a vesicular stomatitis virus nucleocapsid-RNA complex

Template:ABSTRACT PUBMED 16778022

About this Structure

2GIC is a Single protein structure of sequence from Vesicular stomatitis indiana virus. Full crystallographic information is available from OCA.

Reference

Structure of the vesicular stomatitis virus nucleoprotein-RNA complex., Green TJ, Zhang X, Wertz GW, Luo M, Science. 2006 Jul 21;313(5785):357-60. Epub 2006 Jun 15. PMID:16778022

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