1rna

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{{STRUCTURE_1rna| PDB=1rna | SCENE= }}
{{STRUCTURE_1rna| PDB=1rna | SCENE= }}
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'''CRYSTALLOGRAPHIC STRUCTURE OF AN RNA HELIX: [U(U-A)6A]2'''
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===CRYSTALLOGRAPHIC STRUCTURE OF AN RNA HELIX: [U(U-A)6A]2===
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==Overview==
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The crystallographic structure of the synthetic oligoribonucleotide, U(UA)6A, has been solved at 2.25 A resolution. The crystallographic refinement permitted the identification of 91 solvent molecules, with a final agreement factor of 13%. The molecule is a dimer of 14 base-pairs and shows the typical features of an A-type helix. However, the presence of two kinks causes a divergence from a straight helix. The observed deformation, which is stabilized by a few hydrogen bonds in the crystal packing, could be due to the relatively high (35 degrees C) temperature of crystallization. The complete analysis of the structure is presented. It includes the stacking geometries, the backbone conformation and the solvation.
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(as it appears on PubMed at http://www.pubmed.gov), where 2479753 is the PubMed ID number.
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{{ABSTRACT_PUBMED_2479753}}
==About this Structure==
==About this Structure==
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[[Category: A-rna]]
[[Category: A-rna]]
[[Category: Double helix]]
[[Category: Double helix]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul 29 08:08:10 2008''

Revision as of 05:08, 29 July 2008

Template:STRUCTURE 1rna

CRYSTALLOGRAPHIC STRUCTURE OF AN RNA HELIX: [U(U-A)6A]2

Template:ABSTRACT PUBMED 2479753

About this Structure

Full crystallographic information is available from OCA.

Reference

Crystallographic structure of an RNA helix: [U(UA)6A]2., Dock-Bregeon AC, Chevrier B, Podjarny A, Johnson J, de Bear JS, Gough GR, Gilham PT, Moras D, J Mol Biol. 1989 Oct 5;209(3):459-74. PMID:2479753

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